UBC Faculty Research and Publications

TFCat: the curated catalog of mouse and human transcription factors Fulton, Debra L.; Sundararajan, Saravanan; Badis, Gwenael; Hughes, Timothy R.; Wasserman, Wyeth W.; Roach, Jared C.; Sladek, Rob

Abstract

Unravelling regulatory programs governed by transcription factors (TFs) is fundamental to understanding biological systems. TFCat is a catalog of mouse and human TFs based on a reliable core collection of annotations obtained by expert review of the scientific literature. The collection, including proven and homology-based candidate TFs, is annotated within a function-based taxonomy and DNA-binding proteins are organized within a classification system. All data and user-feedback mechanisms are available at the TFCat portal http://www.tfcat.ca .

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Attribution 4.0 International (CC BY 4.0)