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Estimating the impact of expanded access to antiretroviral therapy on maternal, paternal and double orphans in sub-Saharan Africa, 2009-2020 Anema, Aranka; Au-Yeung, Christopher G.; Joffres, Michel; Kaida, Angela; Vasarhelyi, Krisztina; Kanters, Steve; Montaner, Julio; Hogg, Robert S.

Abstract

Background: HIV/AIDS has orphaned 11.6 million children in sub-Saharan Africa. Expanded antiretroviral therapy (ART) use may reduce AIDS orphanhood by decreasing adult mortality and population-level HIV transmission. Methods: We modeled two scenarios to measure the impact of adult ART use on the incidence of orphanhood in 10 sub-Saharan African countries, from 2009 to 2020. Demographic model data inputs were obtained from cohort studies, UNAIDS, UN Population Division, WHO and the US Census Bureau. Results: Compared to current rates of ART uptake, universal ART access averted 4.37 million more AIDS orphans by year 2020, including 3.15 million maternal, 1.89 million paternal and 0.75 million double orphans. The number of AIDS orphans averted was highest in South Africa (901.71 thousand) and Nigeria (839.01 thousand), and lowest in Zimbabwe (86.96 thousand) and Côte d'Ivoire (109.12 thousand). Conclusion: Universal ART use may significantly reduce orphanhood in sub-Saharan Africa.

Item Metadata

Title
Estimating the impact of expanded access to antiretroviral therapy on maternal, paternal and double orphans in sub-Saharan Africa, 2009-2020
Creator
Anema, Aranka; Au-Yeung, Christopher G.; Joffres, Michel; Kaida, Angela; Vasarhelyi, Krisztina; Kanters, Steve; Montaner, Julio; Hogg, Robert S.
Publisher
BioMed Central
Date Issued
2011-03-07
Description
Background: HIV/AIDS has orphaned 11.6 million children in sub-Saharan Africa. Expanded antiretroviral therapy (ART) use may reduce AIDS orphanhood by decreasing adult mortality and population-level HIV transmission. Methods: We modeled two scenarios to measure the impact of adult ART use on the incidence of orphanhood in 10 sub-Saharan African countries, from 2009 to 2020. Demographic model data inputs were obtained from cohort studies, UNAIDS, UN Population Division, WHO and the US Census Bureau. Results: Compared to current rates of ART uptake, universal ART access averted 4.37 million more AIDS orphans by year 2020, including 3.15 million maternal, 1.89 million paternal and 0.75 million double orphans. The number of AIDS orphans averted was highest in South Africa (901.71 thousand) and Nigeria (839.01 thousand), and lowest in Zimbabwe (86.96 thousand) and Côte d'Ivoire (109.12 thousand). Conclusion: Universal ART use may significantly reduce orphanhood in sub-Saharan Africa.
Genre
Article
Type
Text
Language
eng
Date Available
2016-01-12
Provider
Vancouver : University of British Columbia Library
Rights
Attribution 4.0 International (CC BY 4.0)
DOI
10.14288/1.0223346
URI
http://hdl.handle.net/2429/56469
Affiliation
Medicine, Faculty of
Citation
AIDS Research and Therapy. 2011 Mar 07;8(1):13
Publisher DOI
10.1186/1742-6405-8-13
Peer Review Status
Reviewed
Scholarly Level
Faculty
Copyright Holder
Anema et al; licensee BioMed Central Ltd.
Rights URI
http://creativecommons.org/licenses/by/4.0/
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Attribution 4.0 International (CC BY 4.0)