UBC Faculty Research and Publications

Inhaled beta-2 agonist salbutamol and acute lung injury: an association with improvement in acute lung injury Manocha, Sanjay; Gordon, Anthony C; Salehifar, Ebrahim; Groshaus, Horacio; Walley, Keith R; Russell, James A


Introduction: β2 agonists have several properties that could be beneficial in acute lung injury (ALI). We therefore chose to study the effect of inhaled β2 agonist use (salbutamol) on duration and severity of ALI. Methods: We undertook a retrospective chart review of 86 consecutive mechanically ventilated patients with ALI, who had varying exposure to inhaled salbutamol. The cohort was divided into two groups according to the average daily dose of inhaled salbutamol they received ('high dose' ≥ 2.2 mg/day and 'low dose'

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