UBC Faculty Research and Publications

Pathological heterogeneity in amyotrophic lateral sclerosis with FUS mutations : two distinct patterns correlating with disease severity and mutation Mackenzie, Ian; Ansorge, Olaf; Strong, Michael; Bilbao, Juan; Zinman, Lorne; Ang, Lee-Cyn Ang; Baker, Matt; Stewart, Heather; Eisen, Andrew; Rademakers, Rosa; Neumann, Manuela

Abstract

Mutations in the gene encoding the fused in sarcoma (FUS) protein are responsible for ~3% of familial amyotrophic lateral sclerosis (ALS) and

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Attribution-NonCommercial-NoDerivatives 4.0 International