Recent Advances in Metal-Organic Framework (MOF) Asymmetric Membranes/Composites for Biomedical Applications
department or school: Applied Science, Faculty of
department or school: Non UBC
department or school: Engineering, School of (Okanagan)
data provider: DSpace
identifier citation: Symmetry 15 (2): 403 (2023)
contributor: University of British Columbia. Nanomaterials and Polymer Nanocomposites Laboratory
creator: Valizadeh Harzand, Farrokhfar
creator: Mousavi Nejad, Seyyed Navid
creator: Babapoor, Aziz
creator: Mousavi, Seyyed Mojtaba
creator: Hashemi, Seyyed Alireza
creator: Gholami, Ahmad
creator: Chiang, Wei-Hung
creator: Buonomenna, Maria Giovanna
creator: Lai, Chin Wei
issued: 2025-06-23T18:56:14Z
issued: 2023-02-03
description: Metal-organic frameworks (MOFs) are a new class of porous crystalline materials composed of metal and organic material. MOFs have fascinating properties, such as fine tunability, large specific surface area, and high porosity. MOFs are widely used for environmental protection, biosensors, regenerative medicine, medical engineering, cell therapy, catalysts, and drug delivery. Recent studies have reported various significant properties of MOFs for biomedical applications, such as drug detection and delivery. In contrast, MOFs have limitations such as low stability and low specificity in binding to the target. MOF-based membranes improve the stability and specificity of conventional MOFs by increasing the surface area and developing the possibility of MOF-ligand binding, while conjugated membranes dramatically increase the area of active functional groups. This special property makes them attractive for drug and biosensor fabrication, as both the spreading and solubility components of the porosity can be changed. Asymmetric membranes are a structure with high potential in the biomedical field, due to the different characteristics on its two surfaces, the possibility of adjusting various properties such as the size of porosity, transfer rate and selectivity, and surface properties such as hydrophilicity and hydrophobicity. MOF assisted asymmetric membranes can provide a platform with different properties and characteristics in the biomedical field. The latest version of MOF materials/membranes has several potential applications, especially in medical engineering, cell therapy, drug delivery, and regenerative medicine, which will be discussed in this review, along with their advantages, disadvantages, and challenges.
aggregated CHO: https://circle.library.ubc.ca/rest/handle/2429/91403
note: Citation: Valizadeh Harzand, F.;Mousavi Nejad, S.N.; Babapoor, A.;Mousavi, S.M.; Hashemi, S.A.;Gholami, A.; Chiang, W.-H.;Buonomenna, M.G.; Lai, C.W. RecentAdvances in Metal-OrganicFramework (MOF) AsymmetricMembranes/Composites forBiomedical Applications. Symmetry2023, 15, 403. https://doi.org/10.3390/sym15020403Academic Editors: Chong Liu andStefano SuperchiReceived: 25 December 2022Revised: 19 January 2023Accepted: 30 January 2023Published: 3 February 2023Copyright: © 2023 by the authors.Licensee MDPI, Basel, Switzerland.This article is an open access articledistributed under the terms andconditions of the Creative CommonsAttribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).symmetryS SReviewRecent Advances in Metal-Organic Framework (MOF)Asymmetric Membranes/Composites forBiomedical ApplicationsFarrokhfar Valizadeh Harzand 1 , Seyyed Navid Mousavi Nejad 2, Aziz Babapoor 1, Seyyed Mojtaba Mousavi 3,*,Seyyed Alireza Hashemi 4, Ahmad Gholami 5 , Wei-Hung Chiang 3,* , Maria Giovanna Buonomenna 6and Chin Wei Lai 7,*1 Department of Chemical Engineering, University of Mohaghegh Ardabili, Ardabil 56199-11367, Iran2 Department of Clinical Biochemistry, School of Medicine, Shahid Beheshti University of Medical Sciences,Tehran 15167-45811, Iran3 Department of Chemical Engineering, National Taiwan University of Science and Technology,Taipei 106335, Taiwan4 Nanomaterials and Polymer Nanocomposites Laboratory, School of Engineering,University of British Columbia, Kelowna, BC V1V 1V7, Canada5 Biotechnology Research Centre, Shiraz University of Medical Sciences, Shiraz 71348-14336, Iran6 Ordine dei Chimici e Fisici della Campania (OCF) and MIUR, 80134 Napoli, Italy7 Nanotechnology & Catalysis Research Centre, University of Malaya, Kuala Lumpur 50603, Malaysia* Correspondence: mousavi.nano@gmail.com (S.M.M.); whchiang@mail.ntust.edu.tw (W.-H.C.);cwlai@um.edu.my (C.W.L.)Abstract: Metal-organic frameworks (MOFs) are a new class of porous crystalline materials c…
has type: Article
is shown at: 10.14288/1.0449168
language: eng
peer review status: Reviewed
provider: Vancouver : University of British Columbia Library
publisher: Multidisciplinary Digital Publishing Institute
publisher DOI: 10.3390/sym15020403
rights: CC BY 4.0
rights URI: https://creativecommons.org/licenses/by/4.0/
scholar level: Faculty
subject: metal-organic frame works
subject: MOF membrane
subject: drug delivery
subject: cancer therapy
subject: asymmetric membranes
type: Text
identifier URI: http://hdl.handle.net/2429/91403