An Optimization Framework for Silicon Photonic Evanescent-Field Biosensors Using Sub-Wavelength Gratings
department or school: Applied Science, Faculty of
department or school: Other UBC
department or school: Non UBC
department or school: Biomedical Engineering, School of
department or school: Electrical and Computer Engineering, Department of
data provider: DSpace
identifier citation: Biosensors 12 (10): 840 (2022)
contributor: University of British Columbia. Centre for Blood Research
contributor: The Stewart Blusson Quantum Matter Institute
creator: Puumala, Lauren S.
creator: Grist, Samantha M.
creator: Wickremasinghe, Kithmin
creator: Al-Qadasi, Mohammed A.
creator: Chowdhury, Sheri Jahan
creator: Liu, Yifei
creator: Mitchell, Matthew
creator: Chrostowski, Lukas
creator: Shekhar, Sudip
creator: Cheung, Karen C.
issued: 2024-12-17T16:03:34Z
issued: 2022-10-08
description: Silicon photonic (SiP) evanescent-field biosensors aim to combine the information-rich readouts offered by lab-scale diagnostics, at a significantly lower cost, and with the portability and rapid time to result offered by paper-based assays. While SiP biosensors fabricated with conventional strip waveguides can offer good sensitivity for label-free detection in some applications, there is still opportunity for improvement. Efforts have been made to design higher-sensitivity SiP sensors with alternative waveguide geometries, including sub-wavelength gratings (SWGs). However, SWG-based devices are fragile and prone to damage, limiting their suitability for scalable and portable sensing. Here, we investigate SiP microring resonator sensors designed with SWG waveguides that contain a “fishbone” and highlight the improved robustness offered by this design. We present a framework for optimizing fishbone-style SWG waveguide geometries based on numerical simulations, then experimentally measure the performance of ring resonator sensors fabricated with the optimized waveguides, targeting operation in the O-band and C-band. For the O-band and C-band devices, we report bulk sensitivities up to 349 nm/RIU and 438 nm/RIU, respectively, and intrinsic limits of detection as low as 5.1 × 10−⁴ RIU and 7.1 × 10−⁴ RIU, respectively. This performance is comparable to the state of the art in SWG-based sensors, positioning fishbone SWG resonators as an attractive, more robust, alternative to conventional SWG designs.
aggregated CHO: https://circle.library.ubc.ca/rest/handle/2429/89896
note: Citation: Puumala, L.S.; Grist, S.M.;Wickremasinghe, K.; Al-Qadasi, M.A.;Chowdhury, S.J.; Liu, Y.; Mitchell, M.;Chrostowski, L.; Shekhar, S.; Cheung,K.C. An Optimization Framework forSilicon Photonic Evanescent-FieldBiosensors Using Sub-WavelengthGratings. Biosensors 2022, 12, 840.https://doi.org/10.3390/bios12100840Received: 6 September 2022Accepted: 30 September 2022Published: 8 October 2022Publisher’s Note: MDPI stays neutralwith regard to jurisdictional claims inpublished maps and institutional affil-iations.Copyright: © 2022 by the authors.Licensee MDPI, Basel, Switzerland.This article is an open access articledistributed under the terms andconditions of the Creative CommonsAttribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).biosensorsArticleAn Optimization Framework for Silicon PhotonicEvanescent-Field Biosensors Using Sub-Wavelength GratingsLauren S. Puumala 1,2,*, Samantha M. Grist 1,2,3, Kithmin Wickremasinghe 4 , Mohammed A. Al-Qadasi 4,†,cSheri Jahan Chowdhury 4,†, Yifei Liu 4, Matthew Mitchell 3,5 , Lukas Chrostowski 3,4,5, Sudip Shekhar 3,4cand Karen C. Cheung 1,2,4,*1 School of Biomedical Engineering, University of British Columbia, 251-2222 Health Sciences Mall,Vancouver, BC V6T 1Z3, Canada2 Centre for Blood Research, University of British Columbia, 2350 Health Sciences Mall,Vancouver, BC V6T 1Z3, Canada3 Dream Photonics Inc., Vancouver, BC V6T 0A7, Canada4 Department of Electrical and Computer Engineering, University of British Columbia, 5500-2332 Main Mall,Vancouver, BC V6T 1Z4, Canada5 Stewart Blusson Quantum Matter Institute, University of British Columbia, 2355 East Mall,Vancouver, BC V6T 1Z4, Canada* Correspondence: lpuumala@student.ubc.ca (L.S.P.); kcheung@ece.ubc.ca (K.C.C.)† These authors contributed equally to this work.Abstract: Silicon photonic (SiP) evanescent-field biosensors aim to combine the information-richreadouts offered by lab-scale diagnostics, at a significantly lower cost, and with the portability andrapi…
has type: Article
is shown at: 10.14288/1.0447522
language: eng
peer review status: Reviewed
provider: Vancouver : University of British Columbia Library
publisher: Multidisciplinary Digital Publishing Institute
publisher DOI: 10.3390/bios12100840
rights: CC BY 4.0
rights URI: https://creativecommons.org/licenses/by/4.0/
scholar level: Faculty
subject: silicon photonics
subject: evanescent field biosensor
subject: SOI biosensor
subject: ring resonator
subject: fishbone sub-wavelength grating waveguide
subject: sub-wavelength grating waveguide
subject: SWG-assist waveguide
subject: bridged SWG waveguide
subject: microfluidics
type: Text
identifier URI: http://hdl.handle.net/2429/89896