http://dx.doi.org/10.14288/1.0406642
department or school: Applied Science, Faculty of
department or school: Medicine, Faculty of
department or school: Non UBC
department or school: Medicine, Department of
department or school: Nursing, School of
department or school: Population and Public Health (SPPH), School of
data provider: DSpace
identifier citation: Goodyear T, Ti L, Carrieri P, Small W, & Knight R. (2020). “Everybody living with a chronic disease is entitled to be cured”: Challenges and opportunities in scaling up access to direct-acting antiviral hepatitis C virus treatment among people who inject drugs. International Journal of Drug Policy, 81, 102766, 1-8.
contributor: British Columbia Centre on Substance Use
creator: Goodyear, Trevor
creator: Ti, Lianping
creator: Carrieri, Patrizia
creator: Small, Will
creator: Knight, Rod E.
issued: 2022-02-23T16:01:25Z
issued: 2020-03-27
description: Background: Recent advances in the safety, tolerability, and efficacy of hepatitis C virus (HCV) treatments have led to the introduction of policy changes that include, in some settings, universal coverage of direct-acting antiviral (DAA) treatment for people living with HCV. However, people who inject drugs (PWID), a population with disproportionately high rates of HCV, often experience significant social and structural barriers to care, including when seeking treatment and care for blood-borne viruses. The objective of this study is to identify implementation challenges and opportunities for improving HCV-related care and scaling up DAA treatment for PWID living with HCV in a setting with universal DAA coverage since 2018. Methods: Informed by a critical interpretive framework, this study thematically analyzes data from in-depth, semi-structured interviews conducted between October 2018 and February 2019 with a purposive sample of 15 expert stakeholders (e.g., clinicians, community-based organization representatives, policy makers) related to HCV care provision, design, or research in British Columbia, Canada. Results: Our analysis revealed two key thematics: First, participants described existing challenges for scaling up DAA treatment, including how contextual factors (e.g., housing, stigma) restrict opportunities for PWID to engage in care. Participants also described how strained and compartmentalized health services are onerous to navigate for patients. Second, participants described opportunities for improving HCV-related care through various structural interventions (e.g., improved housing, decriminalization of substance use), and enhanced and more accessible models of care (e.g., decentralized, integrated, outreach-focused, and peer- and nurse-led services). Conclusions: These findings emphasize that several key service delivery and system-level adaptations are required in order to equitably scale up access of DAAs to PWID living with HCV, including polici…
aggregated CHO: https://circle.library.ubc.ca/rest/handle/2429/80866
note: Page 1 of 22 “Everybody living with a chronic disease is entitled to be cured”: Challenges and opportunities in scaling up access to direct-acting antiviral hepatitis C virus treatment among people who inject drugs Authors: Trevor Goodyear [1,2,3], Lianping Ti [1,4], Patrizia Carrieri [5,6], Will Small [1,7], Rod Knight [1,4]§ 1. British Columbia Centre on Substance Use, Vancouver, Canada 2. School of Nursing, University of British Columbia, Vancouver, Canada 3. School of Population and Public Health, University of British Columbia, Vancouver, Canada 4. Department of Medicine, University of British Columbia, Vancouver, Canada 5. Aix Marseille Univ, INSERM, IRD, SESSTIM, Sciences Économiques & Sociales de la Santé & Traitement de l’Information Médicale, Marseille, France 6. ORS PACA, Observatoire Régional de la Santé Provence-Alpes-Côte d’Azur, Marseille, France 7. Centre for Applied Research in Mental Health and Addiction, Faculty of Health Sciences, Simon Fraser University, Vancouver, Canada § Corresponding Author: Rod Knight, PhD British Columbia Centre on Substance Use 400-1045 Howe St, Vancouver, BC V6Z 2A9 Email: bccsu-rk@bccsu.ubc.ca Manuscript Version: 20200327 Journal: International Journal of Drug Policy DOI: 10.1016/j.drugpo.2020.102766 Page 2 of 22 ABSTRACT Abstract Word Count (Limit: 150-300): 274 Background: Recent advances in the safety, tolerability, and efficacy of hepatitis C virus (HCV) treatments have led to the introduction of policy changes that include, in some settings, universal coverage of direct-acting antiviral (DAA) treatment for people living with HCV. However, people who inject drugs (PWID), a population with disproportionately high rates of HCV, often experience significant social and structural barriers to care, including when seeking treatment and care for blood-borne viruses. The objective of this study is to identify implementation challenges and opportunities for improving HCV-related care and scaling up DAA treatment for PWID liv…
has type: Article
has type: Postprint
is shown at: 10.14288/1.0406642
language: eng
peer review status: Reviewed
provider: Vancouver : University of British Columbia Library
publisher: Elsevier
publisher DOI: 10.1016/j.drugpo.2020.102766
rights: Attribution-NonCommercial-NoDerivatives 4.0 International
rights URI: http://creativecommons.org/licenses/by-nc-nd/4.0/
scholar level: Faculty
scholar level: Graduate
subject: Hepatitis C
subject: direct-acting antivirals
subject: people who inject drugs
subject: substance use
subject: qualitative research
subject: treatment
title: “Everybody living with a chronic disease is entitled to be cured” : Challenges and opportunities in scaling up access to direct-acting antiviral hepatitis C virus treatment among people who inject drugs
type: Text
identifier URI: http://hdl.handle.net/2429/80866