Association between built environment factors and post-menopausal breast cancer : Alberta’s tomorrow project
department or school: Medicine, Faculty of
department or school: Population and Public Health (SPPH), School of
data provider: DSpace
degree campus: UBCV
creator: Ahmadi, Mohadeseh
issued: 2024-08-20T17:21:13Z
issued: 2024
related degree: Master of Science - MSc
degree grantor: University of British Columbia
description: Background: Breast cancer is the most common cancer in women. Some established risk factors for breast cancer include obesity, physical activity, food choices, smoking, and alcohol use. With increasing rates of urbanization, there might be certain built environment features, such as traffic-related air pollution (TRAP), greenness, and walkability, that influence breast cancer risk. Objective: To assess the impact of TRAP on the risk of post-menopausal breast cancer by utilizing incident breast cancer data from Alberta’s Tomorrow Project (ATP) cohort linked to geographic datasets from the Canadian Urban Environmental Health Research (CANUE). This study will also assess the impact of the built environment factors on the risk breast cancer. Method: This study entailed a secondary analysis of baseline data from the ATP. Cox proportional hazard regression was used to build four models to assess the association between breast cancer risk and built environment factors. Results: The study included 15,536 participants and 523 incident breast cancer cases. The HR estimate for a 10 ppb increase in NO2 measured at baseline (the year participant completed the UHLQ or CORE survey) was 1.10 (95% CI = 0.90, 1.34). For walkability, the adjusted HRs for quintile 2 through 5, in relation to quintile 1, were 1.07 (95% CI = 0.80-1.44), 1.39 (1.05-1.83), 1.49 (1.13-1.97), and 1.22 (0.90-1.66), respectively. Q1 corresponded to least walkable neighbourhoods and Q5 corresponded to most walkable neighbourhoods. The HR estimate for an interquartile range increase in baseline greenness for this model was 1.05 (95% CI = 0.94, 1.16). For greenness measured within 1000 meters, the HR estimate for an IQR increase was 0.97 (95% CI = 0.88, 1.07). Discussion: We found non-significant associations between NO₂ exposure and post-menopausal breast cancer. For walkability, the least walkable areas had the lowest breast cancer rate, and the most walkable areas corresponded to greater breast cancer risk. Fu…
aggregated CHO: https://circle.library.ubc.ca/rest/handle/2429/88089
note: Association between built environment factors and post-menopausal breast cancer: Alberta’s tomorrow project by Mohadeseh Ahmadi BSc, The University of British Columbia, 2021 A THESIS SUBMITTED IN PARTIAL FULFILLMENT OF THE REQUIREMENT FOR THE DEGREE OF MASTER OF SCIENCE in THE FACULTY OF GRADUATE AND POSTDOCTORAL STUDIES (Population and Public Health) THE UNIVERSITY OF BRITISH COLUMBIA (Vancouver) April 2024 Mohadeseh Ahmadi, 2024 ii The following individuals certify that they have read, and recommend to the Faculty of Graduate and Postdoctoral Studies for acceptance, a thesis entitled: Association between built environment factors and post-menopausal breast cancer: Alberta’s tomorrow project submitted by Mohadeseh Ahmadi in partial fulfillment of the requirements for the degree of: Master of Science in Population and Public Health Examining Committee: Dr. Trevor Dummer, Population and Public Health, UBC Supervisor Dr. Maryam Darvishian, Population and Public Health, UBC Supervisory Committee Member Dr. Rachel Murphy, Population and Public Health, UBC Supervisory Committee Member Dr. Chris McLeod, Population and Public Health, UBC Additional Examiner iii Abstract Background: Breast cancer is the most common cancer in women. Some established risk factors for breast cancer include obesity, physical activity, food choices, smoking, and alcohol use. With increasing rates of urbanization, there might be certain built environment features, such as traffic-related air pollution (TRAP), greenness, and walkability, that influence breast cancer risk. Objective: To assess the impact of TRAP on the risk of post-menopausal breast cancer by utilizing incident breast cancer data from Alberta’s Tomorrow Project (ATP) cohort linked to geographic datasets from the Canadian Urban Environmental Health Research (CANUE). This study will also assess the impact of the built environment factors on the risk breast cancer. Method: This study entailed a secondary analysis of baseline data from…
has type: Thesis/Dissertation
date issued: 2024-05
is shown at: 10.14288/1.0442038
language: eng
degree discipline: Population and Public Health
provider: Vancouver : University of British Columbia Library
publisher: University of British Columbia
rights: Attribution-NonCommercial-NoDerivatives 4.0 International
rights URI: http://creativecommons.org/licenses/by-nc-nd/4.0/
scholar level: Graduate
contributor: Dummer, Trevor J. B.
type: Text
identifier URI: http://hdl.handle.net/2429/88089