http://dx.doi.org/10.14288/1.0165802
department or school: Applied Science, Faculty of
department or school: Mechanical Engineering, Department of
data provider: DSpace
degree campus: UBCV
creator: Mustin, Benjamin
issued: 2015-10-24T01:53:22
issued: 2015
related degree: Doctor of Philosophy - PhD
degree grantor: University of British Columbia
description: This thesis investigates several research questions associated with the transport of microscopic particles in microfluidic environments. This includes an investigation of the motion and deposition of micron sized polystyrene particles at the planar polydimethylsiloxane–water interface. Particle tracking shows that particles near the substrate can be immobilized to different degrees. Careful analysis of the more weakly immobilized particles reveals that there is a buildup of a particle accumulation layer near the substrate in which particle motion parallel to the substrate is hindered by non-hydrodynamic effects. The presence of lateral surface interaction forces resulting from charge heterogeneity of the PDMS substrate is found to be the most plausible explanation for the hindered particle transport across the substrate. The two other problems are concerned with micro particle image velocimetry (μPIV), which is a particle transport-based optical method for the characterization of flow fields in microfluidic devices. One limitation μPIV is the finite measurement depth associated with the optical setup, which can lead to bias errors in the measured flow-velocity. Analytical and numerical models are developed that describe the effect of common image pre-processing filters on the measurement depth in μPIV. Further, previous models are revisited that describe the effect of flow velocity gradients on the measurement depth in μPIV.
aggregated CHO: https://circle.library.ubc.ca/rest/handle/2429/54827
note: Particle Transport in Microfluidic Environments: Particle Adsorption at the Polydimethylsiloxane-Water Interface and the Effects of Flow Field and Image Processing on the Measurement Depth in Micro Particle Image Velocimetry by Benjamin Mustin Dipl.-Ingenieur (TH) Technische Universität Dresden, 2010 A THESIS SUBMITTED IN PARTIAL FULLFILLMENT OF THE REQUIREMENTS FOR THE DEGREE OF Doctor of Philosophy in The Faculty of Graduate and Postdoctoral Studies (Mechanical Engineering) THE UNIVERSITY OF BRITISH COLUMBIA (Vancouver) September 2015 © Benjamin MustinAbstract This thesis investigates several research questions associated with the transport of microscopic particles in microfluidic environments. This includes an investigation of the motion and deposition of micron sized polystyrene particles at the planar polydimethylsiloxane–water interface. Particle tracking shows that particles near the substrate can be immobilized to different degrees. Careful analysis of the more weakly immobilized particles reveals that there is a buildup of a particle accumulation layer near the substrate in which particle motion parallel to the substrate is hindered by non-hydrodynamic effects. The presence of lateral surface interaction forces resulting from charge heterogeneity of the PDMS substrate is found to be the most plausible explanation for the hindered particle transport across the substrate. The two other problems are concerned with micro particle image velocimetry (µPIV), which is a particle transport-based optical method for the characterization of flow fields in microfluidic devices. One limitation µPIV is the finite measurement depth associated with the optical setup, which can lead to bias errors in the measured flow-velocity. Analytical and numerical models are developed that describe the effect of common image pre-processing filters on the measurement depth in µPIV. Further, previous models are revisited that describe the effect of flow velocity gradients on the measureme…
has type: Thesis/Dissertation
date issued: 2015-11
is shown at: 10.14288/1.0165802
language: eng
degree discipline: Mechanical Engineering
provider: Vancouver : University of British Columbia Library
publisher: University of British Columbia
rights: Attribution-NonCommercial-NoDerivs 2.5 Canada
rights URI: http://creativecommons.org/licenses/by-nc-nd/2.5/ca/
scholar level: Graduate
title: Particle transport in microfluidic environments : particle adsorption at the polydimethylsiloxane-water interface and the effects of flow field and image processing on the measurement depth in micro particle image velocimetry
type: Text
type: Moving Image
identifier URI: http://hdl.handle.net/2429/54827