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Data from: Phylogenomic diversity of archigregarine apicomplexans Lax, Gordon; Park, Eunji; Na, Ina; Jacko-Reynolds, Victoria; Kwong, Waldan K.; House, Chloe S.E.; Trznadel, Morelia; Wakeman, Kevin; Leander, Brian S.; Keeling, Patrick
Description
<b>Abstract</b><br/>
Gregarines are a large and diverse subgroup of Apicomplexa, a lineage of obligate animal symbionts including pathogens like <em>Plasmodium</em>, the malaria parasite. Unlike <em>Plasmodium</em>, however, gregarines are poorly studied, despite the fact that as early-branching apicomplexans they are crucial to our understanding of the origin and evolution of all apicomplexans and their parasitic lifestyle. Exemplifying this, the earliest branch of gregarines, the archigregarines, are particularly poorly studied: around 80 species have been described from marine invertebrates, but almost all of them were assigned to a single genus, <em>Selenidium</em>. Most are known only from light micrographs and largely unresolved rDNA phylogenies, where they exhibit a great deal of sequence variation, but fall into at least five subclades. To resolve the relationships within archigregarines, we sequenced 12 single-cell transcriptomes from species representing all four known subclades, as well as one blastogregarine (which frequently branch with <em>Selenidium</em>). A 190-gene phylogenomic tree confirmed fourmaximally-supported individual clades of archigregarines and blastogregarines. These clades are discrete and distantly related, and also correlate with host identity. We propose the establishment of three novel genera of archigregarines to reflect their phylogenetic diversity and host range, and nine novel species isolated from a range of marine invertebrates.</p>
Item Metadata
| Title |
Data from: Phylogenomic diversity of archigregarine apicomplexans
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| Creator | |
| Date Issued |
2024-10-10
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| Description |
<b>Abstract</b><br/>
Gregarines are a large and diverse subgroup of Apicomplexa, a lineage of obligate animal symbionts including pathogens like <em>Plasmodium</em>, the malaria parasite. Unlike <em>Plasmodium</em>, however, gregarines are poorly studied, despite the fact that as early-branching apicomplexans they are crucial to our understanding of the origin and evolution of all apicomplexans and their parasitic lifestyle. Exemplifying this, the earliest branch of gregarines, the archigregarines, are particularly poorly studied: around 80 species have been described from marine invertebrates, but almost all of them were assigned to a single genus, <em>Selenidium</em>. Most are known only from light micrographs and largely unresolved rDNA phylogenies, where they exhibit a great deal of sequence variation, but fall into at least five subclades. To resolve the relationships within archigregarines, we sequenced 12 single-cell transcriptomes from species representing all four known subclades, as well as one blastogregarine (which frequently branch with <em>Selenidium</em>). A 190-gene phylogenomic tree confirmed fourmaximally-supported individual clades of archigregarines and blastogregarines. These clades are discrete and distantly related, and also correlate with host identity. We propose the establishment of three novel genera of archigregarines to reflect their phylogenetic diversity and host range, and nine novel species isolated from a range of marine invertebrates.</p> |
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| Notes |
Dryad version number: 5</p> Version status: submitted</p> Dryad curation status: Published</p> Sharing link: http://datadryad.org/stash/dataset/doi:10.5061/dryad.cfxpnvxfg</p> Storage size: 2483458774</p> Visibility: public</p> |
| Date Available |
2024-10-04
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| Provider |
University of British Columbia Library
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| License |
CC0 1.0
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| DOI |
10.14288/1.0445532
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| Publisher DOI | |
| Grant Funding Agency |
Gordon and Betty Moore Foundation; Hakai Institute; Natural Sciences and Engineering Research Council; Fundação para a Ciência e a Tecnologia; Japan Society for the Promotion of Science; Natural Sciences and Engineering Research Council
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| Rights URI | |
| Aggregated Source Repository |
Dataverse
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CC0 1.0