Open Collections

UBC Research Data

Experimental hybridization studies suggest that pleiotropic alleles commonly underlie adaptive divergence between natural populations Thompson, Ken

Description

Abstract

The alleles used for adaptation can pleiotropically affect traits under stabilizing selection. The fixation of alleles with deleterious pleiotropic effects causes compensatory alleles to be favoured by selection. Such compensatory alleles might segregate in interpopulation hybrids, resulting in segregation variance for traits where parents have indistinguishable phenotypes. If adaptation typically involves pleiotropy and compensation, then the segregation variance for traits under stabilizing selection is expected to increase with the magnitude of adaptive phenotypic divergence between parents. This prediction has not been tested empirically, and I gathered data from experimental hybridization studies to evaluate it. I found that pairs of parents which are more phenotypically divergent beget hybrids with more segregation variance in traits for which the parents are statistically indistinguishable. This result suggests that adaptive divergence between pairs of natural populations proceeds via pleiotropy and compensation, and that deleterious transgressive segregation variance accumulates systematically as populations diverge.; Methods

Please see detailed description in appendix of article.

Item Metadata

Title	Experimental hybridization studies suggest that pleiotropic alleles commonly underlie adaptive divergence between natural populations
Creator	Thompson, Ken
Date Issued	2021-05-19
Description	<b>Abstract</b><br/> The alleles used for adaptation can pleiotropically affect traits under stabilizing selection. The fixation of alleles with deleterious pleiotropic effects causes compensatory alleles to be favoured by selection. Such compensatory alleles might segregate in interpopulation hybrids, resulting in segregation variance for traits where parents have indistinguishable phenotypes. If adaptation typically involves pleiotropy and compensation, then the segregation variance for traits under stabilizing selection is expected to increase with the magnitude of adaptive phenotypic divergence between parents. This prediction has not been tested empirically, and I gathered data from experimental hybridization studies to evaluate it. I found that pairs of parents which are more phenotypically divergent beget hybrids with more segregation variance in traits for which the parents are statistically indistinguishable. This result suggests that adaptive divergence between pairs of natural populations proceeds via pleiotropy and compensation, and that deleterious transgressive segregation variance accumulates systematically as populations diverge.</p>; <b>Methods</b><br /> Please see detailed description in appendix of article. </p>
Subject	Other; pleiotropy; segregation variance; Theory
Type	Dataset
Notes	Dryad version number: 1</p> Version status: submitted</p> Dryad curation status: Published</p> Sharing link: https://datadryad.org/stash/share/zGlSsfU2b0GFDs7fiDBrL3isr79kgg8yQdZjbPGjlY0</p> Storage size: 758774</p> Visibility: public</p>
Date Available	2019-12-20
Provider	University of British Columbia Library
License	CC0 1.0
DOI	10.14288/1.0398014
URI	https://doi.org/10.5683/SP2/Y2E644
Publisher DOI	https://doi.org/10.5683/SP2/Y2E644; https://doi.org/10.5061/dryad.qjq2bvqc3
Rights URI	http://creativecommons.org/publicdomain/zero/1.0
Aggregated Source Repository	Dataverse

Item Media

Item Citations and Data

Licence

CC0 1.0