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Data from: The prevalence of MS in the United States: a population-based estimate using health claims data Wallin, Mitchell T.; Culpepper, William J.; Campbell, Jonathan D.; Nelson, Lorene M.; Langer-Gould, Annette; Marrie, Ruth Ann; Cutter, Gary R.; Kaye, Wendy E.; Wagner, Laurie; Tremlett, Helen; et al.
Description
<b>Abstract</b><br/>Objective: To generate a national multiple sclerosis (MS) prevalence estimate for the United States by applying a validated algorithm to multiple administrative health claims (AHC) datasets. Methods: A validated algorithm was applied to private, military, and public AHC datasets to identify adult cases of MS between 2008 and 2010. In each dataset, we determined the 3-year cumulative prevalence overall and stratified by age, sex, and census region. We applied insurance-specific and stratum-specific estimates to the 2010 US Census data and pooled the findings to calculate the 2010 prevalence of MS in the United States cumulated over 3 years. We also estimated the 2010 prevalence cumulated over 10 years using 2 models and extrapolated our estimate to 2017. Results: The estimated 2010 prevalence of MS in the US adult population cumulated over 10 years was 309.2 per 100,000 (95% confidence interval [CI] 308.1–310.1), representing 727,344 cases. During the same time period, the MS prevalence was 450.1 per 100,000 (95% CI 448.1–451.6) for women and 159.7 (95% CI 158.7–160.6) for men (female:male ratio 2.8). The estimated 2010 prevalence of MS was highest in the 55- to 64-year age group. A US north-south decreasing prevalence gradient was identified. The estimated MS prevalence is also presented for 2017. Conclusion: The estimated US national MS prevalence for 2010 is the highest reported to date and provides evidence that the north-south gradient persists. Our rigorous algorithm-based approach to estimating prevalence is efficient and has the potential to be used for other chronic neurologic conditions.; <b>Usage notes</b><br /><div class="o-metadata__file-usage-entry"><h4 class="o-heading__level3-file-title">Prev of MS in the US-E-Appendix-Feb-19-2018</h4><div class="o-metadata__file-name"></div></div>
Item Metadata
Title |
Data from: The prevalence of MS in the United States: a population-based estimate using health claims data
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Creator | |
Date Issued |
2021-05-19
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Description |
<b>Abstract</b><br/>Objective: To generate a national multiple sclerosis (MS) prevalence estimate for the United States by
applying a validated algorithm to multiple administrative health claims (AHC) datasets.
Methods: A validated algorithm was applied to private, military, and public AHC datasets to identify adult
cases of MS between 2008 and 2010. In each dataset, we determined the 3-year cumulative
prevalence overall and stratified by age, sex, and census region. We applied insurance-specific
and stratum-specific estimates to the 2010 US Census data and pooled the findings to calculate
the 2010 prevalence of MS in the United States cumulated over 3 years. We also estimated the
2010 prevalence cumulated over 10 years using 2 models and extrapolated our estimate to 2017.
Results: The estimated 2010 prevalence of MS in the US adult population cumulated over 10 years was
309.2 per 100,000 (95% confidence interval [CI] 308.1–310.1), representing 727,344 cases.
During the same time period, the MS prevalence was 450.1 per 100,000 (95% CI 448.1–451.6)
for women and 159.7 (95% CI 158.7–160.6) for men (female:male ratio 2.8). The estimated
2010 prevalence of MS was highest in the 55- to 64-year age group. A US north-south
decreasing prevalence gradient was identified. The estimated MS prevalence is also presented
for 2017.
Conclusion: The estimated US national MS prevalence for 2010 is the highest reported to date and provides
evidence that the north-south gradient persists. Our rigorous algorithm-based approach to
estimating prevalence is efficient and has the potential to be used for other chronic neurologic
conditions.; <b>Usage notes</b><br /><div class="o-metadata__file-usage-entry"><h4 class="o-heading__level3-file-title">Prev of MS in the US-E-Appendix-Feb-19-2018</h4><div class="o-metadata__file-name"></div></div>
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Notes |
Dryad version number: 1</p> Version status: submitted</p> Dryad curation status: Published</p> Sharing link: https://datadryad.org/stash/share/LjXyJvj619bVE1cpe_NxmWKDnsRvJFeeTJsPgrl2Px8</p> Storage size: 49825</p> Visibility: public</p> |
Date Available |
2020-06-24
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Provider |
University of British Columbia Library
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License |
This dataset is made available under a Creative Commons CC0 license with the following additional/modified terms and conditions: CC0 Waiver
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DOI |
10.14288/1.0397682
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URI | |
Publisher DOI | |
Rights URI | |
Aggregated Source Repository |
Dataverse
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Licence
This dataset is made available under a Creative Commons CC0 license with the following additional/modified terms and conditions: CC0 Waiver