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Data from: Mutational effects depend on ploidy level: all else is not equal Gerstein, Aleeza C.

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Abstract
Ploidy is predicted to influence adaptation directly, yet whether single mutations behave the same in different ploidy backgrounds has not been well studied. It has often been assumed theoretically that aside from dominance, selective parameters do not differ between cells of varying ploidy. Using the budding yeast Saccharomyces cerevisiae, I compared the effect size of 20 adaptive mutations in haploids and homozygous diploids and found, surprisingly, that the same mutations often had a much larger effect in haploids than homozygous diploids. This empirical result demonstrates that it cannot be assumed that mutations will have the same effect in haploids and homozygous diploids.
Usage notes
Tolerance parameter estimates from ML

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Title	Data from: Mutational effects depend on ploidy level: all else is not equal
Creator	Gerstein, Aleeza C.
Date Issued	2021-05-19
Description	Abstract Ploidy is predicted to influence adaptation directly, yet whether single mutations behave the same in different ploidy backgrounds has not been well studied. It has often been assumed theoretically that aside from dominance, selective parameters do not differ between cells of varying ploidy. Using the budding yeast Saccharomyces cerevisiae, I compared the effect size of 20 adaptive mutations in haploids and homozygous diploids and found, surprisingly, that the same mutations often had a much larger effect in haploids than homozygous diploids. This empirical result demonstrates that it cannot be assumed that mutations will have the same effect in haploids and homozygous diploids.; Usage notes Tolerance parameter estimates from ML
Subject	Other; effect size; Dose-response; growth rate
Type	Dataset
Notes	Dryad version number: 1 Version status: submitted Dryad curation status: Published Sharing link: https://datadryad.org/stash/share/60PBtcTj5O758Pewokvciggl7dPtWQUnAWGA0TBZxww</p> Storage size: 85250 Visibility: public
Date Available	2020-06-30
Provider	University of British Columbia Library
License	CC0 1.0
DOI	10.14288/1.0397635
URI	https://doi.org/10.5683/SP2/C9CM31
Publisher DOI	https://doi.org/10.5683/SP2/C9CM31; https://doi.org/10.5061/dryad.h51jg
Rights URI	http://creativecommons.org/publicdomain/zero/1.0
Aggregated Source Repository	Dataverse

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CC0 1.0