[{"key":"dc.contributor.author","value":"Chen, Yanlong","language":null},{"key":"dc.date.accessioned","value":"2026-04-24T05:30:31Z","language":null},{"key":"dc.date.available","value":"2026-04-24T08:03:49Z","language":null},{"key":"dc.date.issued","value":"2026","language":"en"},{"key":"dc.identifier.uri","value":"http:\/\/hdl.handle.net\/2429\/94196","language":null},{"key":"dc.description.abstract","value":"Background: Obstructive sleep apnea (OSA) is commonly treated with oral appliance (OA) therapy, but its effectiveness depends on patient adherence. Although objective microsensor technology now allows accurate measurement of OA use, longitudinal data on adherence patterns and their predictors remain limited. This study aimed to characterize one-year objective adherence to OA therapy in adults with OSA and to identify baseline factors associated with adherence.\r\nMethods: Fifty-five adults with OSA were enrolled in a 12-month prospective observational study. All participants were treated with a custom-made, titratable mandibular advancement device equipped with a temperature-sensitive microsensor to record nightly use. Follow-up visits and data downloads were conducted at 1, 6, and 12 months. Adherent users were defined as those with an average OA use of at least 4 hours per night. Adherence was analyzed using both modified intention-to-treat and per-protocol approaches. Longitudinal changes were assessed over time, and exploratory regression models were used to examine baseline factors associated with adherence.\r\nResults: Twenty-one participants discontinued OA therapy before the 12-month follow-up, leaving 34 who completed the study. At 1 month, 80.0% of patients met the adherence criterion, with a mean wear time of 5.98 \u00b1 2.38 hours\/night. By 6 months, adherence had declined to 67.3%, with mean use of 5.69 \u00b1 2.08 hours\/night. From 6 to 12 months, no further significant change was observed. Among completers, the adherence rate at 12 months was 82.4%, with a mean use of 5.82 \u00b1 2.06 hours\/night. Greater baseline overjet was associated with better adherence at 1-month, older age predicted better adherence at 6 months, and being married or living with a partner was associated with better 12-month adherence. In contrast, baseline psychological disorders were associated with poorer adherence.\r\nConclusions: Objective OA adherence declined mainly during the first 6 months of treatment, with no further significant change between 6 and 12 months. Several baseline factors were associated with adherence, particularly overjet, age, partner status, and psychological comorbidity. These findings highlight the importance of early follow-up and targeted support for patients at risk of poor adaptation to OA therapy.","language":"en"},{"key":"dc.language.iso","value":"eng","language":"en"},{"key":"dc.publisher","value":"University of British Columbia","language":"en"},{"key":"dc.rights","value":"Attribution-NonCommercial-NoDerivatives 4.0 International","language":"*"},{"key":"dc.rights.uri","value":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/","language":"*"},{"key":"dc.title","value":"Objective adherence to oral appliance therapy and influence factors in patients with obstructive sleep apnea : a one-year longitudinal analysis","language":"en"},{"key":"dc.type","value":"Text","language":"en"},{"key":"dc.degree.name","value":"Master of Science - MSc","language":"en"},{"key":"dc.degree.discipline","value":"Craniofacial Science","language":"en"},{"key":"dc.degree.grantor","value":"University of British Columbia","language":"en"},{"key":"dc.contributor.supervisor","value":"Almeida, Fernanda","language":null},{"key":"dc.date.graduation","value":"2026-11","language":"en"},{"key":"dc.type.text","value":"Thesis\/Dissertation","language":"en"},{"key":"dc.description.affiliation","value":"Dentistry, Faculty of","language":"en"},{"key":"dc.degree.campus","value":"UBCV","language":"en"},{"key":"dc.description.scholarlevel","value":"Graduate","language":"en"}]