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Does Body Awareness Mediate the Relationship Between Anxiety and Nocebo Edgington, Brinn; Weik, Ella; Neuenschwander, Regula; Oberlander, Tim; Tipper, Christine 2020-04

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Does Body Awareness Mediate the Relationship Between Anxiety and Nocebo?Brinn Edgington1,2, Ella Weik1,3, Regula Neuenschwander5, Tim Oberlander1,4, & Christine Tipper1,31BC Children’s Hospital Research Institute, 2Department of Psychology, 3Department of Psychiatry, 4Department of Pediatrics,  University of British Columbia, Vancouver, BC, Canada, 5Department of Psychology, University of Bern, Switzerland Introduction• The nocebo effect is defined as negative outcomes produced by negative expectations1• People with higher rates of trait anxiety experience a larger magnitude of the nocebo effect.2• Higher rates of anxiety are also related to a higher awareness of one’s bodily functions, also known as interoceptive awareness.3,4• There is little research looking at a potential relationship between interoceptive awareness, anxiety, and the nocebo effect.Is interoceptive awareness an underlying mechanism for the relationship between anxiety and the nocebo effect?Interoceptive AwarenessParticipants: n = 43, range: 13 – 40, M = 21, (SD = 6.52)Procedure:1. Conditioning visual stimuli 5 with thermal sensationsA significant nocebo effect was found. However, trait anxiety did not predict the nocebo effect. Further research is necessary to better understand the relationship between anxiety and nocebo, and if interoceptive awareness plays a part.1. A significant nocebo effect was found (t(42) = 2.94, p = .005). 2. There was no significant relationship between trait anxiety and nocebo (F(1, 41) = 0.47, p = .498, 𝛽 = -0.06 ). 3. Interoceptive awareness was not significantly related to trait anxiety (F(1, 41) = 1.10, p = .301, 𝛽 = -0.02 ) or the nocebo effect (F(1, 41) = 0.58, p = .452, 𝛽 = 0.51 ).Research QuestionHypothesisMethods ResultsConclusionHeatHeatHeatHeatHeatReferences1Faasse, K. Australian Psychologist (2019), 2Weik et al., In review (2020), 3Stewart et al., Journal of Anxiety Disorders (2001), 4Pollatos et al., International Journal of Psychophysiology (2007), 5Barry, T. et al. Frontiers in Psychology (2014). Trait Anxiety Nocebo Effect2. Questionnaires• STAI: State Trait Anxiety Inventory• MAIA: Multidimensional Assessment of Interoceptive AwarenessCalibration Conditioning Testing050100+++++

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