UBC Undergraduate Research

Various nutrient content on fish intake in pregnant women Wu, Brian Mar 8, 2008

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VARI OUS NUTRI ENT CONTENT ON FI SH I NTAKE I N PREGNANT WOMEN UBC Depar t ment  of  Nut r i t i on BRI AN WU Mar ch 8,  2008 Out l i ne 1. Over vi ew a) Backgr ound b) Resear ch c) Quest i on 2. Met hods 3. Fi ndi ngs 4. Summar y ( comment s, f ut ur e di r ect i on) I nt r oduct i on • Heal t h- r el at ed i mpor t ance of  n- 3 f at t y ac i ds: 1.  Ant i - i nf l ammat or y agent  2.  Neur ol ogi cal heal t h I nt r oduct i on and My Resear ch Quest i on •  Fi sh i s  an abundant sour ce of  nut r i ent s i nc l ude: a.n-3 fatty acids a.Fat soluble vitamins (vitamin A, D, E,) a.Water soluble vitamin (B12, folate) a.Amino acids (cysteine, arginine) a.Iron a. Choline Li mi t at i on of cur r ent  s t udi es on n- 3 ad f i sh i nt ake • Onl y f ocused on n- 3 as t he onl y f act or  t hat cont r i but e t o such benef i t s • Ot her  st udi es on i ndi v i dual  nut r i ent s such as chol i ne show si mi l ar  heal t h benef i t s • Never  i nvest i gat e whet her  t hese heal t h benef i t s ar e cont r i but ed by s i ngl e nut r i ent  or  mul t i pl e nut r i ent s Resear ch Quest i ons • Do peopl e wi t h hi gh f i sh i nt ake have hi gh i nt ake of nut r i ent s ot her  t han n- 3 f at t y aci ds? • Ar e t he heal t h benef i t s  of  f i sh i nt ake cont r i but ed by s i ngl e nut r i ent or  mul t i pl e nut r i ent s? Met hods Subj ect s and Desi gn: Low Meat I nt ake Hi gh Meat I nt ake Low Fi sh I nt ake Gr oup 1 Gr oup 2 Hi gh Fi sh I nt ake Gr oup 3 Gr oup 4 - Compare the differences intake of chosen nutrients among these 4 groups St at i st i cal Anal ys i s -   Tukey’ s mul t i pl e compar i son t est  was used t o det ect s i gni f i cant di f f er ences i n i nt ake of  chosen nut r i ent s among women gr ouped by f i sh i nt ake. Nut r i ent s t hat di f f er ed among t he 4 gr oups (low fish, low meat) (low fish, high meat) (high fish, low meat) (high fish, high meat) EPA (g) 0.04 0.05 0.15 0.16 DHA (g) 0.07 0.08 0.27 0.32 Arginine (g) 2.35 3.36 3.24 4.05 Cysteine (g) 0.89 0.73 0.69 0.86 Vit-D (mg) 206.69 253.41 317.36 336.81 Vit-B12 (mcg) 4.28 4.59 5.84 6.76 Total Choline (mg) 298.74 353.36 483.22 492.83 Di scussi on/ Comme nt s - Compar ed t o gr oup 1 and 2 wi t h gr oup 3 and 4 gener al l y  have a hi gher  i nt ake of t he f ol l owi ng:1.n-3 fatty acids (EPA, DHA) 2.Arginine 3.Vitamin D, B12 4.Choline Di scussi on/ Commen t - n- 3 f at t y aci ds ar e not t he onl y nut r i ent s - Recal l :  Ot her  nut r i ent s al so have ant i - i nf l ammat or y ef f ect - Chol i ne i nt ake i s associ at ed wi t h neur ol ogi cal  devel opment Di scussi on/ Comm ent • Answer s t o my r esear ch quest i ons: 1. Do peopl e wi t h hi gh f i sh i nt ake al so have hi gh i nt ake of  nut r i ent s ot her  t han n- 3 f at t y aci ds? A:   YES 2.  Ar e t he heal t h benef i t s of  f i sh onl y cont r i but ed by n- 3 f at t y aci ds? A:  ehhh…most l i kel y NO Concl usi on - Ot her  t han n- 3: - Fi sh i nt ake al so cor r el at es t o hi gh i nt ake of  chol i ne,  v i t ami n B12, D,  ar gi ni ne - The heal t h benef i t s of hi gh f i sh i nt ake may be mul t i pl e f act or i al THANKS TO… • Dr .  I nni s f or  t he oppor t uni t y • Russel l  f or cont i nui ng gui dance • Mohammad f or  some of t he t echni cal  hel p • Li zzy and Mi chel l e f or  t he power poi nt !

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