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UBC Theses and Dissertations
Antibiotic screening of plants used to treat infectious diseases in Kenya Mutta, Doris N.
Abstract
This thesis presents a documentation of plants used in traditional medicine for infectious diseases in Kenya, followed by an analysis of antimicrobial activities of their methanolic extracts. In the first part of this study discussions were held with herbalists from around the Arabuko Sokoke forest in Kilifi District and various other parts in Kenya. A total of 56 species belonging to 32 families were documented to treat infections of the gastrointestinal tract, skin and sexually transmitted diseases. This documentation effort will contribute towards preservation of the fragile indigenous knowledge currently threatened by influences of modernization. In the second part, a total of 60 extracts from 54 species were tested against selected pathogenic bacteria i.e. the acid fast bacterium - Mycobacterium phlei, four strains of gram positive bacteria -Bacillus subtilis, Staphylococcus aureus K147, S. aureus MR P0017 and Streptococcus faecalis, four strains of gram negative bacteria - Escherichia coli, Pseudomonas aeruginosa H187, P. aeruginosa H188, Salmonella typhimurium and two strains of yeast fungi Candida albicans and Saccharomyces cerevisiae. A total of 43 extracts of 39 nine species were active against at least one microorganism most of them having a strong link between the disease they are used to treat traditionally and the impact on the responsible bacteria and fungi. This linkage provides evidence for the presence of antibiotic substances and establishes, to some extent, the efficacy of the herbal remedies used for infectious diseases.
Item Metadata
Title |
Antibiotic screening of plants used to treat infectious diseases in Kenya
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Creator | |
Publisher |
University of British Columbia
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Date Issued |
1995
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Description |
This thesis presents a documentation of plants used in traditional medicine for
infectious diseases in Kenya, followed by an analysis of antimicrobial activities of their
methanolic extracts. In the first part of this study discussions were held with herbalists
from around the Arabuko Sokoke forest in Kilifi District and various other parts in
Kenya. A total of 56 species belonging to 32 families were documented to treat
infections of the gastrointestinal tract, skin and sexually transmitted diseases. This
documentation effort will contribute towards preservation of the fragile indigenous
knowledge currently threatened by influences of modernization.
In the second part, a total of 60 extracts from 54 species were tested against
selected pathogenic bacteria i.e. the acid fast bacterium - Mycobacterium phlei, four
strains of gram positive bacteria -Bacillus subtilis, Staphylococcus aureus K147, S. aureus
MR P0017 and Streptococcus faecalis, four strains of gram negative bacteria - Escherichia
coli, Pseudomonas aeruginosa H187, P. aeruginosa H188, Salmonella typhimurium and two
strains of yeast fungi Candida albicans and Saccharomyces cerevisiae. A total of 43 extracts
of 39 nine species were active against at least one microorganism most of them having a
strong link between the disease they are used to treat traditionally and the impact on
the responsible bacteria and fungi. This linkage provides evidence for the presence of
antibiotic substances and establishes, to some extent, the efficacy of the herbal remedies
used for infectious diseases.
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Extent |
7058079 bytes
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Genre | |
Type | |
File Format |
application/pdf
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Language |
eng
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Date Available |
2009-02-12
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Provider |
Vancouver : University of British Columbia Library
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Rights |
For non-commercial purposes only, such as research, private study and education. Additional conditions apply, see Terms of Use https://open.library.ubc.ca/terms_of_use.
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DOI |
10.14288/1.0099006
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URI | |
Degree | |
Program | |
Affiliation | |
Degree Grantor |
University of British Columbia
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Graduation Date |
1996-11
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Campus | |
Scholarly Level |
Graduate
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Aggregated Source Repository |
DSpace
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Item Media
Item Citations and Data
Rights
For non-commercial purposes only, such as research, private study and education. Additional conditions apply, see Terms of Use https://open.library.ubc.ca/terms_of_use.