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Data for: Mouse aversion to isoflurane anesthesia using the drop method Bodnar, Maya; Makowska, Joanna; Boyd, Courtney; Schuppli, Catherine; Weary, Daniel

Description

We assessed mouse aversion to isoflurane administered with the drop method at low concentrations, using a light-dark conditioned place aversion (CPA) paradigm. Latency to enter and the duration spent in the dark (+ isoflurane) chamber was recorded and used to calculate a CPA score based on initial and final preference tests. Our results indicate that using the drop method, to administer isoflurane concentrations between 1.7 and 2.7%, can be used to refine current rodent euthanasia methods.

Item Metadata

Title	Data for: Mouse aversion to isoflurane anesthesia using the drop method
Creator	Bodnar, Maya; Makowska, Joanna; Boyd, Courtney; Schuppli, Catherine; Weary, Daniel
Contributor	Bodnar, Maya
Date Issued	2023-10-26
Description	We assessed mouse aversion to isoflurane administered with the drop method at low concentrations, using a light-dark conditioned place aversion (CPA) paradigm. Latency to enter and the duration spent in the dark (+ isoflurane) chamber was recorded and used to calculate a CPA score based on initial and final preference tests. Our results indicate that using the drop method, to administer isoflurane concentrations between 1.7 and 2.7%, can be used to refine current rodent euthanasia methods.
Subject	Medicine, Health and Life Sciences; euthanasia, conditioned place aversion, aversion, drop method, isoflurane, mice
Type	Dataset
Date Available	2023-10-25
Provider	University of British Columbia Library
License	CC0 1.0
DOI	10.14288/1.0437358
URI	https://doi.org/10.5683/SP3/VIURRC
Publisher DOI	https://doi.org/10.5683/SP3/VIURRC
Rights URI	http://creativecommons.org/publicdomain/zero/1.0
Aggregated Source Repository	Dataverse

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CC0 1.0