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A small clinical trial of vaporized cannabis for PTSD : suggestive results and directions for future study Walsh, Zach; Mitchell, Ian; Crosby, Kim; St. Pierre, Michelle; DeClerck, Drew; Ong, Kaye; Lucas, Philippe
Description
The last few decades have seen increasing interest in the use of cannabis for post-traumatic stress disorder (PTSD). Recent attempts to evaluate the clinical efficacy of cannabis for PTSD were inconclusive and generalizability was limited by undesirable features of the study drug. The present clinical trial evaluated the effects of a commercially available chemovar that was delivered by vaporization. The study was designed as a randomized placebo-controlled cross-over study with three conditions; however, only five individuals completed the trial, and analysis of the placebo effect was not possible. Results identified positive changes consistent with medium-sized within-subject effects for cannabis in the treatment of PTSD. Positive trending results and high patient need mandate future studies of cannabis for the treatment of PTSD.
Item Metadata
Title |
A small clinical trial of vaporized cannabis for PTSD : suggestive results and directions for future study
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Creator | |
Contributor | |
Publisher |
BioMed Central
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Date Issued |
2023-09-09
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Description |
The last few decades have seen increasing interest in the use of cannabis for post-traumatic stress disorder (PTSD). Recent attempts to evaluate the clinical efficacy of cannabis for PTSD were inconclusive and generalizability was limited by undesirable features of the study drug. The present clinical trial evaluated the effects of a commercially available chemovar that was delivered by vaporization. The study was designed as a randomized placebo-controlled cross-over study with three conditions; however, only five individuals completed the trial, and analysis of the placebo effect was not possible. Results identified positive changes consistent with medium-sized within-subject effects for cannabis in the treatment of PTSD. Positive trending results and high patient need mandate future studies of cannabis for the treatment of PTSD.
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Subject | |
Type | |
Language |
eng
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Date Available |
2023-11-15
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Provider |
Vancouver : University of British Columbia Library
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Rights |
Attribution 4.0 International (CC BY 4.0)
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DOI |
10.14288/1.0437687
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URI | |
Affiliation | |
Citation |
Trials. 2023 Sep 09;24(1):578
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Publisher DOI |
10.1186/s13063-023-07543-2
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Peer Review Status |
Reviewed
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Scholarly Level |
Faculty; Researcher; Graduate
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Copyright Holder |
BioMed Central Ltd., part of Springer Nature
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Rights URI | |
Aggregated Source Repository |
DSpace
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Item Media
Item Citations and Data
Rights
Attribution 4.0 International (CC BY 4.0)