Open Collections

UBC Faculty Research and Publications

Primary hypertension therapy : after thiazide, an ACEI or an ARB? Therapeutics Initiative (University of British Columbia)

Description

Therapeutics Letter 133 evaluates optimal treatments for primary hypertension using Cochrane systematic review evidence. Conclusions: Low-dose thiazides are the best drug class for starting antihypertensive therapy. ACEIs are the preferred second line treatment. Antihypertensives achieve most of their BP lowering effect at starting or low doses. Reserve ARBs for patients with ACEI cough or angioedema.

Item Metadata

Title
Primary hypertension therapy : after thiazide, an ACEI or an ARB?
Alternate Title
Therapeutics Letter 133
Creator
Therapeutics Initiative (University of British Columbia)
Date Issued
2021-10
Description
Therapeutics Letter 133 evaluates optimal treatments for primary hypertension using Cochrane systematic review evidence. Conclusions: Low-dose thiazides are the best drug class for starting antihypertensive therapy. ACEIs are the preferred second line treatment. Antihypertensives achieve most of their BP lowering effect at starting or low doses. Reserve ARBs for patients with ACEI cough or angioedema.
Subject
Angiotensin-Converting Enzyme Inhibitors; Angiotensin Receptor Antagonists; Antihypertensive Agents; Hypertension; Thiazides
Genre
Other
Type
Text
Language
eng
Notes
The UBC TI is funded by the BC Ministry of Health to provide evidence-based information about drug therapy. We neither formulate nor adjudicate provincial drug policies.
Date Available
2023-06-20
Provider
Vancouver : University of British Columbia Library
Rights
Attribution-NonCommercial-NoDerivatives 4.0 International
DOI
10.14288/1.0433712
URI
http://hdl.handle.net/2429/85122
Affiliation
Medicine, Faculty of; Anesthesiology, Pharmacology and Therapeutics, Department of
Peer Review Status
Reviewed
Scholarly Level
Faculty; Researcher
Rights URI
http://creativecommons.org/licenses/by-nc-nd/4.0/
Aggregated Source Repository
DSpace

Item Media

Item Citations and Data

Rights

Attribution-NonCommercial-NoDerivatives 4.0 International