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Tramadol : Where do we go from here? Therapeutics Initiative (University of British Columbia)

Description

Therapeutics Letter 131 considers the harms and potential benefits of tramadol. Conclusions: Compared with acetaminophen, NSAIDs or other opioids, tramadol has no therapeutic advantage but some disadvantages. Tramadol’s unpredictable metabolism and complex pharmacology are associated with unique and serious adverse effects. As with other opioids, even short prescriptions for tramadol can engender tolerance, dependence, withdrawal, and abuse. Tramadol (+/- acetaminophen) significantly increases costs to patients and insurers.

Item Metadata

Title
Tramadol : Where do we go from here?
Alternate Title
Therapeutics Letter 131
Creator
Therapeutics Initiative (University of British Columbia)
Date Issued
2021-06
Description
Therapeutics Letter 131 considers the harms and potential benefits of tramadol. Conclusions: Compared with acetaminophen, NSAIDs or other opioids, tramadol has no therapeutic advantage but some disadvantages. Tramadol’s unpredictable metabolism and complex pharmacology are associated with unique and serious adverse effects. As with other opioids, even short prescriptions for tramadol can engender tolerance, dependence, withdrawal, and abuse. Tramadol (+/- acetaminophen) significantly increases costs to patients and insurers.
Subject
Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Drug-Related Side Effects and Adverse Reactions; Tramadol
Genre
Other
Type
Text
Language
eng
Notes
The UBC TI is funded by the BC Ministry of Health to provide evidence-based information about drug therapy. We neither formulate nor adjudicate provincial drug policies.
Date Available
2023-06-20
Provider
Vancouver : University of British Columbia Library
Rights
Attribution-NonCommercial-NoDerivatives 4.0 International
DOI
10.14288/1.0433710
URI
http://hdl.handle.net/2429/85120
Affiliation
Medicine, Faculty of; Anesthesiology, Pharmacology and Therapeutics, Department of
Peer Review Status
Reviewed
Scholarly Level
Faculty; Researcher
Rights URI
http://creativecommons.org/licenses/by-nc-nd/4.0/
Aggregated Source Repository
DSpace

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Rights

Attribution-NonCommercial-NoDerivatives 4.0 International