Biosimilars or Biologics : What’s the difference?

UBC Faculty Research and Publications

Biosimilars or Biologics : What’s the difference? Therapeutics Initiative (University of British Columbia)

Description

Therapeutics Letter 123 examines biologics and biosimilars. Conclusions: Biosimilars are not identical to biologics but lie within the variability range of the originator biologic. Government regulators around the world approve biosimilars based on evidence that biosimilars are not inferior to the originator biologic product in terms of safety and effectiveness. Systematic reviews of switching from biologics to biosimilars found no meaningful differences in safety and effectiveness between them. Biosimilars are less expensive than originator biologics.

Item Metadata

Title	Biosimilars or Biologics : What’s the difference?
Alternate Title	Therapeutics Letter 123
Creator	Therapeutics Initiative (University of British Columbia)
Date Issued	2019-10
Description	Therapeutics Letter 123 examines biologics and biosimilars. Conclusions: Biosimilars are not identical to biologics but lie within the variability range of the originator biologic. Government regulators around the world approve biosimilars based on evidence that biosimilars are not inferior to the originator biologic product in terms of safety and effectiveness. Systematic reviews of switching from biologics to biosimilars found no meaningful differences in safety and effectiveness between them. Biosimilars are less expensive than originator biologics.
Subject	Biosimilar Pharmaceuticals; Drug Safety
Genre	Other
Type	Text
Language	eng
Notes	The UBC TI is funded by the BC Ministry of Health to provide evidence-based information about drug therapy. We neither formulate nor adjudicate provincial drug policies.
Date Available	2023-06-20
Provider	Vancouver : University of British Columbia Library
Rights	Attribution-NonCommercial-NoDerivatives 4.0 International
DOI	10.14288/1.0433702
URI	http://hdl.handle.net/2429/85112
Affiliation	Medicine, Faculty of; Anesthesiology, Pharmacology and Therapeutics, Department of
Peer Review Status	Reviewed
Scholarly Level	Faculty; Researcher
Rights URI	http://creativecommons.org/licenses/by-nc-nd/4.0/
Aggregated Source Repository	DSpace

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