Does SPRINT change our approach to blood pressure targets?

UBC Faculty Research and Publications

Does SPRINT change our approach to blood pressure targets? Therapeutics Initiative (University of British Columbia)

Description

Therapeutics Letter 98 reviews Cochrane systematic review evidence in considering whether SPRINT should change the approach to blood pressure targets. Conclusions: At the present time, lower BP targets (≤ 135/85 mmHg) have not been demonstrated to reduce mortality or total serious adverse events as compared with standard BP targets (≤ 140-160/90-100 mmHg). Careful analysis of the SPRINT trial reveals that benefits of a lower blood pressure target in high-risk nondiabetic people do not outweigh harms. Critical appraisal of systematic reviews and clinical trial reports often leads to interpretation and conclusions different from initial impressions.

Item Metadata

Title	Does SPRINT change our approach to blood pressure targets?
Alternate Title	Therapeutics Letter 98
Creator	Therapeutics Initiative (University of British Columbia)
Date Issued	2016-02
Description	Therapeutics Letter 98 reviews Cochrane systematic review evidence in considering whether SPRINT should change the approach to blood pressure targets. Conclusions: At the present time, lower BP targets (≤ 135/85 mmHg) have not been demonstrated to reduce mortality or total serious adverse events as compared with standard BP targets (≤ 140-160/90-100 mmHg). Careful analysis of the SPRINT trial reveals that benefits of a lower blood pressure target in high-risk nondiabetic people do not outweigh harms. Critical appraisal of systematic reviews and clinical trial reports often leads to interpretation and conclusions different from initial impressions.
Subject	Antihypertensive Agents; Blood Pressure; Hypertension
Genre	Other
Type	Text
Language	eng
Notes	The UBC TI is funded by the BC Ministry of Health to provide evidence-based information about drug therapy. We neither formulate nor adjudicate provincial drug policies.
Date Available	2023-06-20
Provider	Vancouver : University of British Columbia Library
Rights	Attribution-NonCommercial-NoDerivatives 4.0 International
DOI	10.14288/1.0433677
URI	http://hdl.handle.net/2429/85087
Affiliation	Medicine, Faculty of; Anesthesiology, Pharmacology and Therapeutics, Department of
Peer Review Status	Reviewed
Scholarly Level	Faculty; Researcher
Rights URI	http://creativecommons.org/licenses/by-nc-nd/4.0/
Aggregated Source Repository	DSpace

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