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Increasing use of newer antipsychotics in children : A cause for concern? Therapeutics Initiative (University of British Columbia)

Description

Therapeutics Letter 74 examines the increasing use of antipsychotics in children. The use of antipsychotics in children and adolescents remains controversial. Understanding the effects of early and possibly long-term exposure to antipsychotics in children is vital given their potential effects on brain and social development. No controlled trial evidence supports the use of any antipsychotics for behavioural conditions such as ADHD. Based on a far larger albeit poor quality body of evidence in adults, previous Therapeutics Letters about olanzapine and quetiapine concluded more evidence on long-term effectiveness and safety of new antipsychotics was needed. In children, early development of obesity or type 2 diabetes may be irreversible. Physicians and parents should be especially cautious and concerned when considering using these drugs in children.

Item Metadata

Title
Increasing use of newer antipsychotics in children : A cause for concern?
Alternate Title
Therapeutics Letter 74
Creator
Therapeutics Initiative (University of British Columbia)
Date Issued
2009-06
Description
Therapeutics Letter 74 examines the increasing use of antipsychotics in children. The use of antipsychotics in children and adolescents remains controversial. Understanding the effects of early and possibly long-term exposure to antipsychotics in children is vital given their potential effects on brain and social development. No controlled trial evidence supports the use of any antipsychotics for behavioural conditions such as ADHD. Based on a far larger albeit poor quality body of evidence in adults, previous Therapeutics Letters about olanzapine and quetiapine concluded more evidence on long-term effectiveness and safety of new antipsychotics was needed. In children, early development of obesity or type 2 diabetes may be irreversible. Physicians and parents should be especially cautious and concerned when considering using these drugs in children.
Subject
Antipsychotic Agents; Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Drug-Related Side Effects and Adverse Reactions; Olanzapine; Quetiapine Fumarate
Genre
Other
Type
Text
Language
eng
Notes
The UBC TI is funded by the BC Ministry of Health to provide evidence-based information about drug therapy. We neither formulate nor adjudicate provincial drug policies.
Date Available
2023-06-20
Provider
Vancouver : University of British Columbia Library
Rights
Attribution-NonCommercial-NoDerivatives 4.0 International
DOI
10.14288/1.0433653
URI
http://hdl.handle.net/2429/85063
Affiliation
Medicine, Faculty of; Anesthesiology, Pharmacology and Therapeutics, Department of
Peer Review Status
Reviewed
Scholarly Level
Faculty; Researcher
Rights URI
http://creativecommons.org/licenses/by-nc-nd/4.0/
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Attribution-NonCommercial-NoDerivatives 4.0 International