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The Answer : Thiazides First-line for Hypertension Therapeutics Initiative (University of British Columbia)

Description

Therapeutics Letter 47 reviews first-line treatments for hypertension. Conclusions: Total mortality, coronary heart disease and end-stage renal disease are similar for first-line thiazides, CCBs and ACEIs. Heart failure is increased with first-line CCBs as compared to thiazides or ACEIs. Stroke is reduced with first-line thiazides as compared to ACEIs. BP control and tolerability are better with first-line thiazides as compared to ACEIs. Cost is substantially less for thiazides as compared to beta-blockers, ACEIs, CCBs, alpha blockers, and angiotensin receptor blockers.

Item Metadata

Title
The Answer : Thiazides First-line for Hypertension
Alternate Title
Therapeutics Letter 47
Creator
Therapeutics Initiative (University of British Columbia)
Date Issued
2003-03
Description
Therapeutics Letter 47 reviews first-line treatments for hypertension. Conclusions: Total mortality, coronary heart disease and end-stage renal disease are similar for first-line thiazides, CCBs and ACEIs. Heart failure is increased with first-line CCBs as compared to thiazides or ACEIs. Stroke is reduced with first-line thiazides as compared to ACEIs. BP control and tolerability are better with first-line thiazides as compared to ACEIs. Cost is substantially less for thiazides as compared to beta-blockers, ACEIs, CCBs, alpha blockers, and angiotensin receptor blockers.
Subject
Antihypertensive Agents; Drug Costs; Hypertension; Patient Safety; Thiazides
Genre
Other
Type
Text
Language
eng
Notes
The UBC TI is funded by the BC Ministry of Health to provide evidence-based information about drug therapy. We neither formulate nor adjudicate provincial drug policies.
Date Available
2023-06-20
Provider
Vancouver : University of British Columbia Library
Rights
Attribution-NonCommercial-NoDerivatives 4.0 International
DOI
10.14288/1.0433626
URI
http://hdl.handle.net/2429/85036
Affiliation
Medicine, Faculty of; Anesthesiology, Pharmacology and Therapeutics, Department of
Peer Review Status
Reviewed
Scholarly Level
Faculty; Researcher
Rights URI
http://creativecommons.org/licenses/by-nc-nd/4.0/
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Attribution-NonCommercial-NoDerivatives 4.0 International