UBC Faculty Research and Publications

Levels of Evidence for Clinical Decisions : Menopausal Hormone Therapy Revisited Therapeutics Initiative (University of British Columbia)

Description

Therapeutics Letter 30 examines levels of evidence for clinical decision-making in the context of menopausal hormone therapy (HT). Conclusions: Is the controversy over prescribing HT resolved by the Heart and Estrogen/progestin Replacement Study (HERS) trial? Probably not. Recent publications, while including the HERS trial in their list of references, are still advising doctors to encourage use of HT for prevention of CHD and osteoporosis. It will likely take some time for the full implications of the Level I evidence from the HERS trial to be reflected in the literature and practice.

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Attribution-NonCommercial-NoDerivatives 4.0 International