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Angiotensin II Receptor Blockers : Their role in hypertension and congestive heart failure Therapeutics Initiative (University of British Columbia)

Description

Therapeutics Letter 28 explores the role of angiotensin II receptor blockers in hypertension and congestive heart failure. Conclusions: Angiotensin receptor blockers act to modulate the renin angiotensin pathway at a different site compared to ACE inhibitors. There is suggestive evidence that angiotensin receptor blockers may not be as good at lowering blood pressure as ACE inhibitors. Because they are not associated with the intractable dry cough seen in some patients taking ACE inhibitors, angiotensin receptor blockers are indicated in patients who require an ACE inhibitor (see Therapeutics Letter 8) but who cannot tolerate it due to drug-induced dry cough.

Item Metadata

Title
Angiotensin II Receptor Blockers : Their role in hypertension and congestive heart failure
Alternate Title
Therapeutics Letter 28
Creator
Therapeutics Initiative (University of British Columbia)
Date Issued
1999-03
Description
Therapeutics Letter 28 explores the role of angiotensin II receptor blockers in hypertension and congestive heart failure. Conclusions: Angiotensin receptor blockers act to modulate the renin angiotensin pathway at a different site compared to ACE inhibitors. There is suggestive evidence that angiotensin receptor blockers may not be as good at lowering blood pressure as ACE inhibitors. Because they are not associated with the intractable dry cough seen in some patients taking ACE inhibitors, angiotensin receptor blockers are indicated in patients who require an ACE inhibitor (see Therapeutics Letter 8) but who cannot tolerate it due to drug-induced dry cough.
Subject
 Angiotensin Receptor Antagonists; Antihypertensive Agents; Heart Failure; Hypertension
Genre
Other
Type
Text
Language
eng
Notes
The UBC TI is funded by the BC Ministry of Health to provide evidence-based information about drug therapy. We neither formulate nor adjudicate provincial drug policies.
Date Available
2023-06-20
Provider
Vancouver : University of British Columbia Library
Rights
Attribution-NonCommercial-NoDerivatives 4.0 International
DOI
10.14288/1.0433607
URI
http://hdl.handle.net/2429/85017
Affiliation
Medicine, Faculty of; Anesthesiology, Pharmacology and Therapeutics, Department of
Peer Review Status
Reviewed
Scholarly Level
Faculty; Researcher
Rights URI
http://creativecommons.org/licenses/by-nc-nd/4.0/
Aggregated Source Repository
DSpace

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Attribution-NonCommercial-NoDerivatives 4.0 International