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New drugs 2 Therapeutics Initiative (University of British Columbia)

Description

Therapeutics Letter 17 reviews the five newer drugs famciclovir, valacyclovir, torsemide, etodolac, and naltrexone. Conclusions: Anti-viral drugs have a modest beneficial effect if given early (rash <72 hr) to immunocompetent patients (>50 yr) with moderate to severe rash or pain associated with acute herpes zoster (shingles). Torsemide is a new loop diuretic which is more potent and longer acting than furosemide; however, at present there are no demonstrated therapeutic advantages of torsemide. Etodolac is a new NSAID which has similar effectiveness to other available NSAIDs. It may prove to have a relatively low incidence of serious GI toxicity, however more data are required. Naltrexone is a pure long acting orally active opioid antagonist which may prove effective as an adjunct in opioid and alcohol dependence treatment programs.

Item Metadata

Title
New drugs 2
Alternate Title
Therapeutics Letter 17
Creator
Therapeutics Initiative (University of British Columbia)
Date Issued
1997-01
Description
Therapeutics Letter 17 reviews the five newer drugs famciclovir, valacyclovir, torsemide, etodolac, and naltrexone. Conclusions: Anti-viral drugs have a modest beneficial effect if given early (rash <72 hr) to immunocompetent patients (>50 yr) with moderate to severe rash or pain associated with acute herpes zoster (shingles). Torsemide is a new loop diuretic which is more potent and longer acting than furosemide; however, at present there are no demonstrated therapeutic advantages of torsemide. Etodolac is a new NSAID which has similar effectiveness to other available NSAIDs. It may prove to have a relatively low incidence of serious GI toxicity, however more data are required. Naltrexone is a pure long acting orally active opioid antagonist which may prove effective as an adjunct in opioid and alcohol dependence treatment programs.
Subject
Anti-Inflammatory Agents, Non-Steroidal; Antiviral Agents; Etodolac; Famciclovir; Naltrexone; Pain; Torsemide; Valacyclovir
Genre
Other
Type
Text
Language
eng
Notes
The UBC TI is funded by the BC Ministry of Health to provide evidence-based information about drug therapy. We neither formulate nor adjudicate provincial drug policies.
Date Available
2023-06-20
Provider
Vancouver : University of British Columbia Library
Rights
Attribution-NonCommercial-NoDerivatives 4.0 International
DOI
10.14288/1.0433596
URI
http://hdl.handle.net/2429/85006
Affiliation
Medicine, Faculty of; Anesthesiology, Pharmacology and Therapeutics, Department of
Peer Review Status
Reviewed
Scholarly Level
Faculty; Researcher
Rights URI
http://creativecommons.org/licenses/by-nc-nd/4.0/
Aggregated Source Repository
DSpace

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Attribution-NonCommercial-NoDerivatives 4.0 International