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Dose Titration : Dose Minimize to Maximize Therapeutics Initiative (University of British Columbia)

Description

Therapeutics Letter 10 examines dose titration and the problems with using product monographs when considering the appropriate introductory doses for medications. Conclusions: For those patients who do not require an immediate response (hypertension, NIDDM, osteoarthritis, hyperlipidemia), start with a dose that is a 1/4 to 1/2 the recommended starting dose in the Compendium of Pharmaceuticals and Specialties (CPS). Due to unpredictable responses in individual patients, the initial prescription for almost all drugs should be roughly 1-2 weeks to prevent unnecessary wastage in the patient who cannot tolerate the drug. The duration of subsequent prescriptions should be based on the need for future follow up.

Item Metadata

Title
Dose Titration : Dose Minimize to Maximize
Alternate Title
Therapeutics Letter 10
Creator
Therapeutics Initiative (University of British Columbia)
Date Issued
1995-10
Description
Therapeutics Letter 10 examines dose titration and the problems with using product monographs when considering the appropriate introductory doses for medications. Conclusions: For those patients who do not require an immediate response (hypertension, NIDDM, osteoarthritis, hyperlipidemia), start with a dose that is a 1/4 to 1/2 the recommended starting dose in the Compendium of Pharmaceuticals and Specialties (CPS). Due to unpredictable responses in individual patients, the initial prescription for almost all drugs should be roughly 1-2 weeks to prevent unnecessary wastage in the patient who cannot tolerate the drug. The duration of subsequent prescriptions should be based on the need for future follow up.
Subject
Diabetes Mellitus, Type 2; Hyperlipidemias; Hypertension; Osteoarthritis; Prescriptions
Genre
Other
Type
Text
Language
eng
Notes
The UBC TI is funded by the BC Ministry of Health to provide evidence-based information about drug therapy. We neither formulate nor adjudicate provincial drug policies.
Date Available
2023-06-20
Provider
Vancouver : University of British Columbia Library
Rights
Attribution-NonCommercial-NoDerivatives 4.0 International
DOI
10.14288/1.0433590
URI
http://hdl.handle.net/2429/84999
Affiliation
Medicine, Faculty of; Anesthesiology, Pharmacology and Therapeutics, Department of
Peer Review Status
Reviewed
Scholarly Level
Faculty; Researcher
Rights URI
http://creativecommons.org/licenses/by-nc-nd/4.0/
Aggregated Source Repository
DSpace

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Attribution-NonCommercial-NoDerivatives 4.0 International