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Drugs of Choice in the Treatment of Hypertension : Part 1 Therapeutics Initiative (University of British Columbia)

Description

Therapeutics Letter 7 examines drugs of choice for the treatment of hypertension. Conclusions: based on the evidence available at this time and using criteria of effectiveness and cost, thiazides are clearly the drug of first choice. Based on the criteria of efficacy, tolerability and convenience, thiazides are equivalent to or better than all other drugs. Therefore, thiazides are the drug of first choice for most uncomplicated hypertensive patients. There will be a proportion of patients (20-25%) where thiazides are proven ineffective or inappropriate. In these patients or in patients requiring more than one drug, other drugs must be substituted or added. These other drugs will be discussed in Therapeutics Letter 8.

Item Metadata

Title
Drugs of Choice in the Treatment of Hypertension : Part 1
Alternate Title
Therapeutics Letter 7
Creator
Therapeutics Initiative (University of British Columbia)
Date Issued
1995-06
Description
Therapeutics Letter 7 examines drugs of choice for the treatment of hypertension. Conclusions: based on the evidence available at this time and using criteria of effectiveness and cost, thiazides are clearly the drug of first choice. Based on the criteria of efficacy, tolerability and convenience, thiazides are equivalent to or better than all other drugs. Therefore, thiazides are the drug of first choice for most uncomplicated hypertensive patients. There will be a proportion of patients (20-25%) where thiazides are proven ineffective or inappropriate. In these patients or in patients requiring more than one drug, other drugs must be substituted or added. These other drugs will be discussed in Therapeutics Letter 8.
Subject
Antihypertensive Agents; Drug Costs; Hypertension; Patient Safety; Thiazides
Genre
Other
Type
Text
Language
eng
Notes
The UBC TI is funded by the BC Ministry of Health to provide evidence-based information about drug therapy. We neither formulate nor adjudicate provincial drug policies.
Date Available
2023-06-20
Provider
Vancouver : University of British Columbia Library
Rights
Attribution-NonCommercial-NoDerivatives 4.0 International
DOI
10.14288/1.0433587
URI
http://hdl.handle.net/2429/84996
Affiliation
Medicine, Faculty of; Anesthesiology, Pharmacology and Therapeutics, Department of
Peer Review Status
Reviewed
Scholarly Level
Faculty; Researcher
Rights URI
http://creativecommons.org/licenses/by-nc-nd/4.0/
Aggregated Source Repository
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Attribution-NonCommercial-NoDerivatives 4.0 International