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Protruding Nanostructured Surfaces for Antimicrobial and Osteogenic Titanium Implants Ishak, Mohd I.; Liu, Xiayi; Jenkins, Joshua; Nobbs, Angela H.; Su, Bo

Abstract

Protruding nanostructured surfaces have gained increasing interest due to their unique wetting behaviours and more recently their antimicrobial and osteogenic properties. Rapid development in nanofabrication techniques that offer high throughput and versatility on titanium substrate open up the possibility for better orthopaedic and dental implants that deter bacterial colonisation while promoting osteointegration. In this review we present a brief overview of current problems associated with bacterial infection of titanium implants and of efforts to fabricate titanium implants that have both bactericidal and osteogenic properties. All of the proposed mechano-bactericidal mechanisms of protruding nanostructured surfaces are then considered so as to explore the potential advantages and disadvantages of adopting such novel technologies for use in future implant applications. Different nanofabrication methods that can be utilised to fabricate such nanostructured surfaces on titanium substrate are briefly discussed.

Item Metadata

Title
Protruding Nanostructured Surfaces for Antimicrobial and Osteogenic Titanium Implants
Creator
Ishak, Mohd I.; Liu, Xiayi; Jenkins, Joshua; Nobbs, Angela H.; Su, Bo
Publisher
Multidisciplinary Digital Publishing Institute
Date Issued
2020-08-03
Description
Protruding nanostructured surfaces have gained increasing interest due to their unique wetting behaviours and more recently their antimicrobial and osteogenic properties. Rapid development in nanofabrication techniques that offer high throughput and versatility on titanium substrate open up the possibility for better orthopaedic and dental implants that deter bacterial colonisation while promoting osteointegration. In this review we present a brief overview of current problems associated with bacterial infection of titanium implants and of efforts to fabricate titanium implants that have both bactericidal and osteogenic properties. All of the proposed mechano-bactericidal mechanisms of protruding nanostructured surfaces are then considered so as to explore the potential advantages and disadvantages of adopting such novel technologies for use in future implant applications. Different nanofabrication methods that can be utilised to fabricate such nanostructured surfaces on titanium substrate are briefly discussed.
Subject
nanostructured surfaces; antimicrobial; bactericidal; osteogenic; medical implants
Genre
Article
Type
Text
Language
eng
Date Available
2020-08-24
Provider
Vancouver : University of British Columbia Library
Rights
CC BY 4.0
DOI
10.14288/1.0392931
URI
http://hdl.handle.net/2429/75638
Affiliation
Other UBC; Non UBC
Citation
Coatings 10 (8): 756 (2020)
Publisher DOI
10.3390/coatings10080756
Peer Review Status
Reviewed
Scholarly Level
Faculty
Rights URI
https://creativecommons.org/licenses/by/4.0/
Aggregated Source Repository
DSpace

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CC BY 4.0