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Statins proven and associated harms Therapeutics Initiative (University of British Columbia)

Description

Therapeutics Letter 89 examines proven and associated harms with statin use. Proven harms are those that have been established in systematic reviews or randomized controlled trials (RCTs); associated harms are those identified from observational studies, case series and case reports. Conclusions: The action of statins to reduce many compounds in addition to cholesterol is problematic. Harms with statins are often subtle, usually dose related, sometimes serious and require vigilance to detect. The magnitude of most statins harms remains uncertain at this time. It is essential to weigh the potential benefits and the potential harms in all patients taking or being considered for statin therapy.

Item Metadata

Title
Statins proven and associated harms
Alternate Title
Therapeutics Letter 89
Creator
Therapeutics Initiative (University of British Columbia)
Date Issued
2014-05
Description
Therapeutics Letter 89 examines proven and associated harms with statin use. Proven harms are those that have been established in systematic reviews or randomized controlled trials (RCTs); associated harms are those identified from observational studies, case series and case reports. Conclusions: The action of statins to reduce many compounds in addition to cholesterol is problematic. Harms with statins are often subtle, usually dose related, sometimes serious and require vigilance to detect. The magnitude of most statins harms remains uncertain at this time. It is essential to weigh the potential benefits and the potential harms in all patients taking or being considered for statin therapy.
Subject
Drug-Related Side Effects and Adverse Reactions; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Patient Safety
Genre
Other
Type
Text
Language
eng
Notes
The UBC TI is funded by the BC Ministry of Health to provide evidence-based information about drug therapy. We neither formulate nor adjudicate provincial drug policies.
Date Available
2023-06-20
Provider
Vancouver : University of British Columbia Library
Rights
Attribution-NonCommercial-NoDerivatives 4.0 International
DOI
10.14288/1.0433668
URI
http://hdl.handle.net/2429/85078
Affiliation
Medicine, Faculty of; Anesthesiology, Pharmacology and Therapeutics, Department of
Peer Review Status
Reviewed
Scholarly Level
Faculty; Researcher
Rights URI
http://creativecommons.org/licenses/by-nc-nd/4.0/
Aggregated Source Repository
DSpace

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Attribution-NonCommercial-NoDerivatives 4.0 International