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Central Sensitization Inventory in endometriosis Orr, Natasha L.; Wahl, Kate; Lisonek, Michelle; Joannou, Angela; Noga, Heather; Albert, Arianne; Bedaiwy, Mohamed Ali, 1968-; Williams, Christina; Allaire, Catherine; Yong, Paul J.

Abstract

A key clinical problem is identifying the endometriosis patient whose pain is complicated by central nervous system sensitization, where conventional gynecologic treatment (e.g. hormonal therapy or surgery) may not completely alleviate the pain. The Central Sensitization Inventory (CSI) is a questionnaire previously validated in the chronic pain population. The objective of this study was an exploratory proof-of-concept to identify a CSI cut-off in the endometriosis population to discriminate between individuals with significant central contributors (identified by central sensitivity syndromes (CSS)) to their pain compared to those without. We analyzed a prospective data registry at a tertiary referral center for endometriosis, and included subjects aged 18-50 years with endometriosis who were newly or re-referred to the center in 2018. The study sample consisted of 335 subjects with a mean age of 36.0±7.0 years. An increasing number of CSS was significantly correlated with dysmenorrhea, deep dyspareunia, dyschezia, and chronic pelvic pain scores (p’s

Item Metadata

Title
Central Sensitization Inventory in endometriosis
Creator
Orr, Natasha L.; Wahl, Kate; Lisonek, Michelle; Joannou, Angela; Noga, Heather; Albert, Arianne; Bedaiwy, Mohamed Ali, 1968-; Williams, Christina; Allaire, Catherine; Yong, Paul J.
Contributor
Women's Health Research Institute (British Columbia); BC Women's Hospital and Health Centre
Date Issued
2022-02
Description
A key clinical problem is identifying the endometriosis patient whose pain is complicated by central nervous system sensitization, where conventional gynecologic treatment (e.g. hormonal therapy or surgery) may not completely alleviate the pain. The Central Sensitization Inventory (CSI) is a questionnaire previously validated in the chronic pain population. The objective of this study was an exploratory proof-of-concept to identify a CSI cut-off in the endometriosis population to discriminate between individuals with significant central contributors (identified by central sensitivity syndromes (CSS)) to their pain compared to those without. We analyzed a prospective data registry at a tertiary referral center for endometriosis, and included subjects aged 18-50 years with endometriosis who were newly or re-referred to the center in 2018. The study sample consisted of 335 subjects with a mean age of 36.0±7.0 years. An increasing number of CSS was significantly correlated with dysmenorrhea, deep dyspareunia, dyschezia, and chronic pelvic pain scores (p’s
Subject
Central sensitization; Central Sensitization Inventory; Dysmenorrhea; Endometriosis; Irritable bowel syndrome; Painful bladder syndrome; Dyspareunia
Genre
Article; Postprint
Type
Text
Language
eng
Date Available
2023-04-26
Provider
Vancouver : University of British Columbia Library
Rights
Attribution-NonCommercial-NoDerivatives 4.0 International
DOI
10.14288/1.0431424
URI
http://hdl.handle.net/2429/84488
Affiliation
Medicine, Faculty of; Non UBC; Obstetrics and Gynaecology, Department of
Citation
Orr, Natasha L.; Wahl, Kate J.; Lisonek, Michelle; Joannou, Angela; Noga, Heather; Albert, Arianne; Bedaiwy, Mohamed A.; Williams, Christina; Allaire, Catherine; Yong, Paul J.. Central sensitization inventory in endometriosis. PAIN 163(2):p e234-e245, February 2022.
Publisher DOI
10.1097/j.pain.0000000000002351
Peer Review Status
Reviewed
Scholarly Level
Faculty; Researcher; Postdoctoral
Rights URI
http://creativecommons.org/licenses/by-nc-nd/4.0/
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Attribution-NonCommercial-NoDerivatives 4.0 International