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High-sensitivity C-reactive protein and low-density lipoprotein cholesterol association with incident of cardiovascular events: Isfahan cohort study Nafari, Amirhossein; Mohammadifard, Noushin; Haghighatdoost, Fahimeh; Nasirian, Shima; Najafian, Jamshid; Sadeghi, Masoumeh; Roohafza, Hamidreza; Sarrafzadegan, Nizal

Abstract

Abstract Background There are many studies on high-sensitivity C-reactive protein (hs-CRP) association with cardiovascular disease (CVD); however, just a few studies investigated whether the low-density lipoprotein cholesterol (LDL-C) could participate in hs-CRP prognostic strength. This study aimed to determine the alliance of hs-CRP and LDL-C in different concentrations in occurrence cardiovascular events in the Isfahan Cohort Study (ICS). Methods 3277 participants aged 35 and above were included in the current analysis. We evaluated the association of elevated hs-CRP levels (≥ 3 mg/dL) and CVD events including myocardial infarction, ischemic heart disease, stroke, CVD, CVD mortality, and all-cause mortality in those with LDL-C ≥ or 

Item Metadata

Title
High-sensitivity C-reactive protein and low-density lipoprotein cholesterol association with incident of cardiovascular events: Isfahan cohort study
Creator
Nafari, Amirhossein; Mohammadifard, Noushin; Haghighatdoost, Fahimeh; Nasirian, Shima; Najafian, Jamshid; Sadeghi, Masoumeh; Roohafza, Hamidreza; Sarrafzadegan, Nizal
Publisher
BioMed Central
Date Issued
2022-05-25
Description
Abstract Background There are many studies on high-sensitivity C-reactive protein (hs-CRP) association with cardiovascular disease (CVD); however, just a few studies investigated whether the low-density lipoprotein cholesterol (LDL-C) could participate in hs-CRP prognostic strength. This study aimed to determine the alliance of hs-CRP and LDL-C in different concentrations in occurrence cardiovascular events in the Isfahan Cohort Study (ICS). Methods 3277 participants aged 35 and above were included in the current analysis. We evaluated the association of elevated hs-CRP levels (≥ 3 mg/dL) and CVD events including myocardial infarction, ischemic heart disease, stroke, CVD, CVD mortality, and all-cause mortality in those with LDL-C ≥ or 
Subject
Cardiovascular disease; High-sensitivity C-reactive protein; Low-density lipoprotein cholesterol
Genre
Article
Type
Text
Language
eng
Date Available
2022-09-20
Provider
Vancouver : University of British Columbia Library
Rights
Attribution 4.0 International (CC BY 4.0)
DOI
10.14288/1.0420163
URI
http://hdl.handle.net/2429/82728
Affiliation
Medicine, Faculty of; Non UBC; Population and Public Health (SPPH), School of
Citation
BMC Cardiovascular Disorders. 2022 May 25;22(1):241
Publisher DOI
10.1186/s12872-022-02663-0
Peer Review Status
Reviewed
Scholarly Level
Faculty; Researcher
Copyright Holder
The Author(s)
Rights URI
http://creativecommons.org/licenses/by/4.0/
Aggregated Source Repository
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Rights

Attribution 4.0 International (CC BY 4.0)