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Normal sex and age-specific parameters in a multi-ethnic population: a cardiovascular magnetic resonance study of the Canadian Alliance for Healthy Hearts and Minds cohort Luu, Judy M.; Gebhard, Catherine; Ramasundarahettige, Chinthanie; Desai, Dipika; Schulze, Karleen; Marcotte, Francois; Awadalla, Philip; Broet, Philippe; Dummer, Trevor J. B.; Hicks, Jason; Larose, Eric; Moody, Alan; Smith, Eric E.; Tardif, Jean-Claude; Teixeira, Tiago; Teo, Koon K.; Vena, Jennifer; Lee, Douglas S.; Anand, Sonia S.; Friedrich, Matthias G.

Abstract

Background Despite the growing utility of cardiovascular magnetic resonance (CMR) for cardiac morphology and function, sex and age-specific normal reference values derived from large, multi-ethnic data sets are lacking. Furthermore, most available studies use a simplified tracing methodology. Using a large cohort of participants without history of cardiovascular disease (CVD) or risk factors from the Canadian Alliance for Healthy Heart and Minds, we sought to establish a robust set of reference values for ventricular and atrial parameters using an anatomically correct contouring method, and to determine the influence of age and sex on ventricular parameters. Methods and results Participants (n = 3206, 65% females; age 55.2 ± 8.4 years for females and 55.1 ± 8.8 years for men) underwent CMR using standard methods for quantitative measurements of cardiac parameters. Normal ventricular and atrial reference values are provided: (1) for males and females, (2) stratified by four age categories, and (3) for different races/ethnicities. Values are reported as absolute, indexed to body surface area, or height. Ventricular volumes and mass were significantly larger for males than females (p 

Item Metadata

Title
Normal sex and age-specific parameters in a multi-ethnic population: a cardiovascular magnetic resonance study of the Canadian Alliance for Healthy Hearts and Minds cohort
Creator
Luu, Judy M.; Gebhard, Catherine; Ramasundarahettige, Chinthanie; Desai, Dipika; Schulze, Karleen; Marcotte, Francois; Awadalla, Philip; Broet, Philippe; Dummer, Trevor J. B.; Hicks, Jason; Larose, Eric; Moody, Alan; Smith, Eric E.; Tardif, Jean-Claude; Teixeira, Tiago; Teo, Koon K.; Vena, Jennifer; Lee, Douglas S.; Anand, Sonia S.; Friedrich, Matthias G.
Contributor
BC Cancer Research Centre
Publisher
BioMed Central
Date Issued
2022-01-03
Description
Background Despite the growing utility of cardiovascular magnetic resonance (CMR) for cardiac morphology and function, sex and age-specific normal reference values derived from large, multi-ethnic data sets are lacking. Furthermore, most available studies use a simplified tracing methodology. Using a large cohort of participants without history of cardiovascular disease (CVD) or risk factors from the Canadian Alliance for Healthy Heart and Minds, we sought to establish a robust set of reference values for ventricular and atrial parameters using an anatomically correct contouring method, and to determine the influence of age and sex on ventricular parameters. Methods and results Participants (n = 3206, 65% females; age 55.2 ± 8.4 years for females and 55.1 ± 8.8 years for men) underwent CMR using standard methods for quantitative measurements of cardiac parameters. Normal ventricular and atrial reference values are provided: (1) for males and females, (2) stratified by four age categories, and (3) for different races/ethnicities. Values are reported as absolute, indexed to body surface area, or height. Ventricular volumes and mass were significantly larger for males than females (p 
Subject
Sex; Age; Cardiovascular magnetic resonance; Reference; Normal
Genre
Article
Type
Text
Language
eng
Date Available
2022-01-26
Provider
Vancouver : University of British Columbia Library
Rights
Attribution 4.0 International (CC BY 4.0)
DOI
10.14288/1.0406356
URI
http://hdl.handle.net/2429/80730
Affiliation
Medicine, Faculty of; Non UBC; Population and Public Health (SPPH), School of
Citation
Journal of Cardiovascular Magnetic Resonance. 2022 Jan 03;24(1):2
Publisher DOI
10.1186/s12968-021-00819-z
Peer Review Status
Reviewed
Scholarly Level
Faculty; Researcher
Copyright Holder
The Author(s)
Rights URI
http://creativecommons.org/licenses/by/4.0/
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DSpace

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Rights

Attribution 4.0 International (CC BY 4.0)