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Hydroxychloroquine-induced hyperpigmentation in a 14-year-old female with systemic lupus erythematosus Leung, Alexander K. C.; McMillan, Tara; Human, Andrea; Lam, Joseph

Abstract

Hydroxychloroquine (HCQ)-induced hyperpigmentation is uncommon but is increasingly recognized. To our knowledge, HCQ-induced hyperpigmentation has not been reported in the pediatric age group. Herein, we present the case of a 14-yearold girl with systemic lupus erythematosus, who developed hyperpigmentation on her shins and dorsum of the left foot, approximately 3 years after initiating treatment with HCQ. Physicians who treat children with HCQ for reasons such as rheumatologic disorders, dermatologic disorders and, more recently, coronavirus disease-19 should be aware of this less-known side effect of HCQ.

Item Metadata

Title
Hydroxychloroquine-induced hyperpigmentation in a 14-year-old female with systemic lupus erythematosus
Creator
Leung, Alexander K. C.; McMillan, Tara; Human, Andrea; Lam, Joseph
Contributor
Children's Hospital (Vancouver, B.C.)
Publisher
BioExcel Publishing
Date Issued
2020-07-20
Description
Hydroxychloroquine (HCQ)-induced hyperpigmentation is uncommon but is increasingly recognized. To our knowledge, HCQ-induced hyperpigmentation has not been reported in the pediatric age group. Herein, we present the case of a 14-yearold girl with systemic lupus erythematosus, who developed hyperpigmentation on her shins and dorsum of the left foot, approximately 3 years after initiating treatment with HCQ. Physicians who treat children with HCQ for reasons such as rheumatologic disorders, dermatologic disorders and, more recently, coronavirus disease-19 should be aware of this less-known side effect of HCQ.
Subject
Chloroquine; COVID-19; Dermatologic disorders; Melanin; Rheumatologic disorders
Genre
Article
Type
Text
Language
eng
Date Available
2021-06-17
Provider
Vancouver : University of British Columbia Library
Rights
Attribution-NonCommercial-NoDerivatives 4.0 International
DOI
10.14288/1.0398458
URI
http://hdl.handle.net/2429/78715
Affiliation
Medicine, Faculty of; Non UBC; Dermatology and Skin Science, Department of
Citation
Leung AKC, McMillan T, Human A, Lam JM. Hydroxychloroquineinduced hyperpigmentation in a 14-year-old female with systemic lupus erythematosus. Drugs in Context 2020; 9: 2020-5-8.
Publisher DOI
10.7573/dic.2020-5-8
Peer Review Status
Reviewed
Scholarly Level
Faculty; Researcher
Rights URI
http://creativecommons.org/licenses/by-nc-nd/4.0/
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Attribution-NonCommercial-NoDerivatives 4.0 International