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Serum omentin-1 level in patients with benign prostatic hyperplasia He, Haiqing; Wu, Shuiqing; Hao, Jun; Wang, Long; Ai, Kai; Zhu, Xuan; Xu, Ran; Zhao, Xiaokun; Wang, Yinhuai; Zhong, Zhaohui

Abstract

Backgroud: To evaluate the relationship between omentin-1 and benign prostatic hyperplasia (BPH). BPH is the most common urological disease in elderly men worldwide. Lower serum omentin-1 levels were reported to be negatively associated with the incidence of inflammation, diabetes, obesity and metabolic syndrome, which all play a role in the development of BPH. To the best of our knowledge, the relationship between omentin-1 and BPH has not been investigated previously. Methods: A total of 70 males participated in this study, including forty patients diagnosed with BPH and thirty healthy males. The anthropometric measurements and the biochemical parameters were measured in this study. We evaluated serum omentin-1 levels and the correlation with those data. We also test the gene expression of IL-8, IL-18 in BPH group using the TURP tissues. Results: The serum omentin-1 levels were lower in the BPH patients than in the control group (27.95 ± 4.18 versus 32.03 ± 5.46, p 

Item Metadata

Title
Serum omentin-1 level in patients with benign prostatic hyperplasia
Creator
He, Haiqing; Wu, Shuiqing; Hao, Jun; Wang, Long; Ai, Kai; Zhu, Xuan; Xu, Ran; Zhao, Xiaokun; Wang, Yinhuai; Zhong, Zhaohui
Contributor
Vancouver Prostate Centre
Publisher
BioMed Central
Date Issued
2020-05-06
Description
Backgroud: To evaluate the relationship between omentin-1 and benign prostatic hyperplasia (BPH). BPH is the most common urological disease in elderly men worldwide. Lower serum omentin-1 levels were reported to be negatively associated with the incidence of inflammation, diabetes, obesity and metabolic syndrome, which all play a role in the development of BPH. To the best of our knowledge, the relationship between omentin-1 and BPH has not been investigated previously. Methods: A total of 70 males participated in this study, including forty patients diagnosed with BPH and thirty healthy males. The anthropometric measurements and the biochemical parameters were measured in this study. We evaluated serum omentin-1 levels and the correlation with those data. We also test the gene expression of IL-8, IL-18 in BPH group using the TURP tissues. Results: The serum omentin-1 levels were lower in the BPH patients than in the control group (27.95 ± 4.18 versus 32.03 ± 5.46, p 
Subject
Benign prostatic hyperplasia (BPH); Omentin/Omentin-1; Adipokine; Prostate volume; Interleukin-8; Interleukin-18
Genre
Article
Type
Text
Language
eng
Date Available
2020-05-07
Provider
Vancouver : University of British Columbia Library
Rights
Attribution 4.0 International (CC BY 4.0)
DOI
10.14288/1.0390416
URI
http://hdl.handle.net/2429/74361
Affiliation
Medicine, Faculty of; Other UBC; Non UBC; Urologic Sciences, Department of
Citation
BMC Urology. 2020 May 06;20(1):52
Publisher DOI
10.1186/s12894-020-00623-4
Peer Review Status
Reviewed
Scholarly Level
Faculty
Copyright Holder
The Author(s)
Rights URI
http://creativecommons.org/licenses/by/4.0/
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Attribution 4.0 International (CC BY 4.0)