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Antimicrobial use among adult inpatients at hospital sites within the Canadian Nosocomial Infection Surveillance Program: 2009 to 2016 Rudnick, Wallis; Science, Michelle; Thirion, Daniel J. G.; Abdesselam, Kahina; Choi, Kelly B.; Pelude, Linda; Amaratunga, Kanchana; Comeau, Jeannette L.; Dalton, Bruce; Delport, Johan; Dhami, Rita; Embree, Joanne; Émond, Yannick; Evans, Gerald; Frenette, Charles; Fryters, Susan; German, Greg; Grant, Jennifer M.; Happe, Jennifer; Katz, Kevin; Kibsey, Pamela; Kosar, Justin; Langley, Joanne M.; Lee, Bonita E.; Lefebvre, Marie-Astrid; Leis, Jerome A.; McGeer, Allison; Neville, Heather L.; Simor, Andrew; Slayter, Kathryn; Suh, Kathryn N.; Tse-Chang, Alena; Weiss, Karl; Conly, John

Abstract

Background: Antimicrobial resistance is a growing threat to the world’s ability to prevent and treat infections. Links between quantitative antibiotic use and the emergence of bacterial resistance are well documented. This study presents benchmark antimicrobial use (AMU) rates for inpatient adult populations in acute-care hospitals across Canada. Methods: In this retrospective surveillance study, acute-care adult hospitals participating in the Canadian Nosocomial Infection Surveillance Program (CNISP) submitted annual AMU data on all systemic antimicrobials from 2009 to 2016. Information specific to intensive care units (ICUs) and non-ICU wards were available for 2014–2016. Data were analyzed using defined daily doses (DDD) per 1000 patient days (DDD/1000pd). Results: Between 2009 and 2016, 16–18 CNISP adult hospitals participated each year and provided their AMU data (22 hospitals participated in ≥1 year of surveillance; 11 in all years). From 2009 to 2016, there was a significant reduction in use (12%) (from 654 to 573 DDD/1000pd, p = 0.03). Fluoroquinolones accounted for the majority of this decrease (47% reduction in combined oral and intravenous use, from 129 to 68 DDD/1000pd, p 

Item Metadata

Title
Antimicrobial use among adult inpatients at hospital sites within the Canadian Nosocomial Infection Surveillance Program: 2009 to 2016
Creator
Rudnick, Wallis; Science, Michelle; Thirion, Daniel J. G.; Abdesselam, Kahina; Choi, Kelly B.; Pelude, Linda; Amaratunga, Kanchana; Comeau, Jeannette L.; Dalton, Bruce; Delport, Johan; Dhami, Rita; Embree, Joanne; Émond, Yannick; Evans, Gerald; Frenette, Charles; Fryters, Susan; German, Greg; Grant, Jennifer M.; Happe, Jennifer; Katz, Kevin; Kibsey, Pamela; Kosar, Justin; Langley, Joanne M.; Lee, Bonita E.; Lefebvre, Marie-Astrid; Leis, Jerome A.; McGeer, Allison; Neville, Heather L.; Simor, Andrew; Slayter, Kathryn; Suh, Kathryn N.; Tse-Chang, Alena; Weiss, Karl; Conly, John
Publisher
BioMed Central
Date Issued
2020-02-13
Description
Background: Antimicrobial resistance is a growing threat to the world’s ability to prevent and treat infections. Links between quantitative antibiotic use and the emergence of bacterial resistance are well documented. This study presents benchmark antimicrobial use (AMU) rates for inpatient adult populations in acute-care hospitals across Canada. Methods: In this retrospective surveillance study, acute-care adult hospitals participating in the Canadian Nosocomial Infection Surveillance Program (CNISP) submitted annual AMU data on all systemic antimicrobials from 2009 to 2016. Information specific to intensive care units (ICUs) and non-ICU wards were available for 2014–2016. Data were analyzed using defined daily doses (DDD) per 1000 patient days (DDD/1000pd). Results: Between 2009 and 2016, 16–18 CNISP adult hospitals participated each year and provided their AMU data (22 hospitals participated in ≥1 year of surveillance; 11 in all years). From 2009 to 2016, there was a significant reduction in use (12%) (from 654 to 573 DDD/1000pd, p = 0.03). Fluoroquinolones accounted for the majority of this decrease (47% reduction in combined oral and intravenous use, from 129 to 68 DDD/1000pd, p 
Subject
Antimicrobial use; Hospital; Surveillance
Genre
Article
Type
Text
Language
eng
Date Available
2020-02-14
Provider
Vancouver : University of British Columbia Library
Rights
Attribution 4.0 International (CC BY 4.0)
DOI
10.14288/1.0388630
URI
http://hdl.handle.net/2429/73534
Affiliation
Other UBC; Non UBC
Citation
Antimicrobial Resistance & Infection Control. 2020 Feb 13;9(1):32
Publisher DOI
10.1186/s13756-020-0684-2
Peer Review Status
Reviewed
Scholarly Level
Faculty
Copyright Holder
The Author(s).
Rights URI
http://creativecommons.org/licenses/by/4.0/
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Attribution 4.0 International (CC BY 4.0)