Title	Dynamical and stochastic simulations of knotted and linked DNA
Creator	Swigon, David
Publisher	Banff International Research Station for Mathematical Innovation and Discovery
Date Issued	2021-06-15T09:45
Description	Presented will be two methods that allow the study of the stochastic and dynamical behavior of knotted and confined DNA molecules. One method is based on exact statistical sampling of closed configurations, the other on dynamical simulations performed using on generalized immersed boundary method. The equations of motion of the rod include the fluidâ structure interaction, sequence-dependent elasticity and a combination of two interactions that prevent self-contact, namely the electrostatic interaction and hard-core repulsion. I will discuss the dynamics of DNA trefoils and configurations of DNA Hopf links with relevance to kinetoplast DNA.
Extent	30.0 minutes
Subject	Mathematics; Biology And Other Natural Sciences; Mechanics Of Particles And Systems; Applied Mathematics
Type	Moving Image
File Format	video/mp4
Language	eng
Notes	Author affiliation: University of Pittsburgh
Series	BIRS Workshop Lecture Videos (Banff, Alta)
Date Available	2023-10-27
Provider	Vancouver : University of British Columbia Library
Rights	Attribution-NonCommercial-NoDerivatives 4.0 International
DOI	10.14288/1.0437366
URI	http://hdl.handle.net/2429/86352
Affiliation	Non UBC
Peer Review Status	Unreviewed
Scholarly Level	Researcher
Rights URI	http://creativecommons.org/licenses/by-nc-nd/4.0/
Aggregated Source Repository	DSpace

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