BIRS Workshop Lecture Videos

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BIRS Workshop Lecture Videos

Dynamical and stochastic simulations of knotted and linked DNA Swigon, David


Presented will be two methods that allow the study of the stochastic and dynamical behavior of knotted and confined DNA molecules. One method is based on exact statistical sampling of closed configurations, the other on dynamical simulations performed using on generalized immersed boundary method. The equations of motion of the rod include the fluidâ structure interaction, sequence-dependent elasticity and a combination of two interactions that prevent self-contact, namely the electrostatic interaction and hard-core repulsion. I will discuss the dynamics of DNA trefoils and configurations of DNA Hopf links with relevance to kinetoplast DNA.

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