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Estimating the division of amyloid fibrils Doumic, Marie
Description
Amyloid fibrils are important biological structures associated with devastating human diseases such as Alzheimer disease, as well as have vital biological functions such as adhesion and biofilm formation. The division of amyloid protein fibrils is required for the propagation of the amyloid state and is an important contributor to their stability, pathogenicity, and normal function. We apply asymptotic results on the fragmentation equation to develop an inverse problem approach, allowing us to compare the division stability of amyloid fibrils and estimate their division features (fragmentation rate and kernel). </p>
This is a joint work with Magali Tournus, Miguel Escobedo and Wei-Feng Xue.</p>
Item Metadata
Title |
Estimating the division of amyloid fibrils
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Creator | |
Publisher |
Banff International Research Station for Mathematical Innovation and Discovery
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Date Issued |
2020-11-26T08:26
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Description |
Amyloid fibrils are important biological structures associated with devastating human diseases such as Alzheimer disease, as well as have vital biological functions such as adhesion and biofilm formation. The division of amyloid protein fibrils is required for the propagation of the amyloid state and is an important contributor to their stability, pathogenicity, and normal function. We apply asymptotic results on the fragmentation equation to develop an inverse problem approach, allowing us to compare the division stability of amyloid fibrils and estimate their division features (fragmentation rate and kernel). </p> This is a joint work with Magali Tournus, Miguel Escobedo and Wei-Feng Xue.</p> |
Extent |
23.0 minutes
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Subject | |
Type | |
File Format |
video/mp4
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Language |
eng
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Notes |
Author affiliation: INRIA
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Series | |
Date Available |
2021-05-26
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Provider |
Vancouver : University of British Columbia Library
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Rights |
Attribution-NonCommercial-NoDerivatives 4.0 International
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DOI |
10.14288/1.0398152
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URI | |
Affiliation | |
Peer Review Status |
Unreviewed
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Scholarly Level |
Researcher
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Rights URI | |
Aggregated Source Repository |
DSpace
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Item Media
Item Citations and Data
Rights
Attribution-NonCommercial-NoDerivatives 4.0 International