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scNMT-seq:MOSAIC, or Multi-Omic Supervised Integrative Clustering Arora, Arshi

Description

Arshi Arora is a Research Biostatistician in Dr. Ronglai Shen's lab at Memorial Sloan Kettering Cancer Center, https://www.mskcc.org/profile/arshi-arora Her research addressed the following question; We wish to address the problem of identifying localized molecular signatures with respect to an outcome of interest such as stage and lineage. This poses an interesting challenge in understanding heterogeneity in cell populations across multiple data modalities. We aim to illustrate that the application of a supervised integrative clustering will provide a more accurate delineation of cell subpopulation across genomic, epigenomic, and transcriptomic landscape that is directly relevant to the biological outcome of interest. Code is available at https://github.com/arorarshi/scNMT_seq_MOSAIC

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