BIRS Workshop Lecture Videos

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BIRS Workshop Lecture Videos

scNMT-seq: multivariate integrative analyses Abadi, Al


Dr. Al J Abadi is a Research Fellow and software developer in Computational Genomics in the lab of Prof Kim-Anh Lê Cao at the University of Melbourne, Australia ( He addressed the challenges of i) Identification of multi-omics signatures that characterize lineage, stage or both: We applied a regularised partial least square analysis which can find key markers which characterize the coordinated lineage and stage-specific changes in different modalities ii) Dealing with missing values: In integrative analyses, we applied an iterative algorithm which can handle missing values without potentially inducing spurious correlations in the datasets while allowing for select for variables that are correlated across data modalities and characterize the stage and/or lineage of the cells Code:

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