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CORTEX seq-FISH: selection of spatial coherent genes Xu, Hang


Dr Hang Xu is a postdoctoral Fellow in Christina Curtis's Lab (Stanford). Hang obtained her PhD in bioinformatics at the University of Nottingham, UK. She then trained as a postdoctoral research fellow in the Francis Crick Institute with Charles Swanton. Hang is interested in studying cancer evolutionary dynamics. Her research asked the following questions; 1. Can scRNA-seq data be overlaid onto seqFISH for resolution enhancement 2. What is the minimal number of genes needed for data integration She followed the approaches that described in Zhu's paper (Zhu et al 2018) which integrated scRNAseq and smFISH data. By following the approach, she randomly selected a subset of differently expressed genes and applied a SVM model to estimated the minimal number of genes that are required data integration. Code is available at

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