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Tumors versus T-cells, a simple co-evolutionary model Levine, Herbert
Description
Recent advances in immunotherapy have brought to the fore questions regarding the conditions under which the adaptive immune system can recognize and eliminate cancer cells. Here we introduce a simple model of at the competition between detection and invasion and apply it to recent data from the TRACERX experiments. Our model produces interesting hypotheses regarding the age=dependence of cancer incidence and the ratio of cancer incidence "attempts" versus actual progression to detectable tumors.
Item Metadata
Title |
Tumors versus T-cells, a simple co-evolutionary model
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Creator | |
Publisher |
Banff International Research Station for Mathematical Innovation and Discovery
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Date Issued |
2019-08-23T10:19
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Description |
Recent advances in immunotherapy have brought to the fore questions regarding the conditions under which the adaptive immune system can recognize and eliminate cancer cells. Here we introduce a simple model of at the competition between detection and invasion and apply it to recent data from the TRACERX experiments. Our model produces interesting hypotheses regarding the age=dependence of cancer incidence and the ratio of cancer incidence "attempts" versus actual progression to detectable tumors.
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Extent |
65.0 minutes
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Subject | |
Type | |
File Format |
video/mp4
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Language |
eng
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Notes |
Author affiliation: Northeaster University
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Series | |
Date Available |
2020-02-20
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Provider |
Vancouver : University of British Columbia Library
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Rights |
Attribution-NonCommercial-NoDerivatives 4.0 International
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DOI |
10.14288/1.0388669
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URI | |
Affiliation | |
Peer Review Status |
Unreviewed
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Scholarly Level |
Faculty
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Rights URI | |
Aggregated Source Repository |
DSpace
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Item Media
Item Citations and Data
Rights
Attribution-NonCommercial-NoDerivatives 4.0 International