BIRS Workshop Lecture Videos
Tumors versus T-cells, a simple co-evolutionary model Levine, Herbert
Recent advances in immunotherapy have brought to the fore questions regarding the conditions under which the adaptive immune system can recognize and eliminate cancer cells. Here we introduce a simple model of at the competition between detection and invasion and apply it to recent data from the TRACERX experiments. Our model produces interesting hypotheses regarding the age=dependence of cancer incidence and the ratio of cancer incidence "attempts" versus actual progression to detectable tumors.
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