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A liquid crystal model for DNA packing in bacteriophages Arsuaga, Javier
Description
A modeling framework of genome packing inside bacteriophage capsids is developed and tested. The main assumptions of the model are the chromonic columnar hexagonal structure of confined (ds)DNA and its high resistance to bending. The model has the capability to predict pressure and ejection force as well as the size of the disordered core. It also accounts for the phase transition from solid to fluid-like states as the concentration of DNA in the capsid decreases.
Work in collaboration with C. Calderer, L. Hiltner, M. Vazquez and S. Walker
Item Metadata
Title |
A liquid crystal model for DNA packing in bacteriophages
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Creator | |
Publisher |
Banff International Research Station for Mathematical Innovation and Discovery
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Date Issued |
2019-03-29T09:00
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Description |
A modeling framework of genome packing inside bacteriophage capsids is developed and tested. The main assumptions of the model are the chromonic columnar hexagonal structure of confined (ds)DNA and its high resistance to bending. The model has the capability to predict pressure and ejection force as well as the size of the disordered core. It also accounts for the phase transition from solid to fluid-like states as the concentration of DNA in the capsid decreases.
Work in collaboration with C. Calderer, L. Hiltner, M. Vazquez and S. Walker |
Extent |
31.0 minutes
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Subject | |
Type | |
File Format |
video/mp4
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Language |
eng
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Notes |
Author affiliation: University of California, Davis
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Series | |
Date Available |
2019-09-26
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Provider |
Vancouver : University of British Columbia Library
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Rights |
Attribution-NonCommercial-NoDerivatives 4.0 International
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DOI |
10.14288/1.0381007
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URI | |
Affiliation | |
Peer Review Status |
Unreviewed
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Scholarly Level |
Faculty
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Rights URI | |
Aggregated Source Repository |
DSpace
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Item Media
Item Citations and Data
Rights
Attribution-NonCommercial-NoDerivatives 4.0 International