Title	Algorithms for Inferring Evolution and Migration of Tumors
Creator	Raphael, Ben
Publisher	Banff International Research Station for Mathematical Innovation and Discovery
Date Issued	2017-03-28T11:18
Description	Cancer is an evolutionary process driven by somatic mutations that accumulate in a population of cells that form a primary tumor. In later stages of cancer progression, cells migrate from a primary tumor and seed metastases at distant anatomical sites. I will describe algorithms to reconstruct this evolutionary process from DNA sequencing data of tumors. These algorithms address challenges that distinguish the tumor phylogeny problem from classical phylogenetic tree reconstruction, including challenges due to mixed samples and complex migration patterns. Joint work with Mohammed El-Kebir and Gryte Satas
Extent	27.0
Subject	Mathematics; Statistics; Biology and other natural sciences
Type	Moving Image
File Format	video/mp4
Language	eng
Notes	Author affiliation: Princeton University
Series	BIRS Workshop Lecture Videos (Banff, Alta)
Date Available	2019-03-12
Provider	Vancouver : University of British Columbia Library
Rights	Attribution-NonCommercial-NoDerivatives 4.0 International
DOI	10.14288/1.0376770
URI	http://hdl.handle.net/2429/68608
Affiliation	Non UBC
Peer Review Status	Unreviewed
Scholarly Level	Faculty
Rights URI	http://creativecommons.org/licenses/by-nc-nd/4.0/
Aggregated Source Repository	DSpace

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