Title	Dynamic models for Lipid Bilayers: from Biosensing to Electroporation
Creator	Krishnamurthy, Vikram
Publisher	Banff International Research Station for Mathematical Innovation and Discovery
Date Issued	2016-08-29T11:04
Description	We discuss and evaluate models for the dynamics of two novel measurement platforms: (i) a Pore Formation Measurement Platform (PFMP) for detecting the presence of pore forming proteins and peptides, (ii) the Ion Channel Switch (ICS) biosensor for detecting the presence of analyte molecules in a fluid chamber. Common to both measurement platforms is that they are comprised of an engineered tethered membrane. The electrical response is modelled using continuum theories for electrodiffusive flow coupled with boundary conditions for modelling chemical reactions and electrical double layers present at the bioelectronic interface. Experimental measurements are used to validate the predictive accuracy of the dynamic models.
Extent	20 minutes
Subject	Mathematics; Quantum theory; Mechanics of deformable solids; Applied analysis / inverse problems
Type	Moving Image
File Format	video/mp4
Language	eng
Notes	Author affiliation: University of British Columbia
Series	BIRS Workshop Lecture Videos (Banff, Alta)
Date Available	2017-02-27
Provider	Vancouver : University of British Columbia Library
Rights	Attribution-NonCommercial-NoDerivatives 4.0 International
DOI	10.14288/1.0343006
URI	http://hdl.handle.net/2429/60729
Affiliation	Non UBC
Peer Review Status	Unreviewed
Scholarly Level	Faculty
Rights URI	http://creativecommons.org/licenses/by-nc-nd/4.0/
Aggregated Source Repository	DSpace

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Dynamic models for Lipid Bilayers: from Biosensing to Electroporation Krishnamurthy, Vikram

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