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Using Networks to Probe Biological Systems Quackenbush, John
Description
As new technologies are providing us with ever-richer, more complex data sets that capture diverse yet complementary information about biological systems, our challenge is to move beyond simple correlations and explore the complex networks that drive biological systems. I will draw upon separate, but interwoven threads of network analysis that have proven very fruitful in our work, including inference and comparison of gene regulatory networks using a message-passing framework, exploring the diversity and distribution of networks within a phenotype and in state transitions, and exploring the structure of networks as a means of interpreting the factors driving complex, multifactorial phenotypes.
Item Metadata
Title |
Using Networks to Probe Biological Systems
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Creator | |
Publisher |
Banff International Research Station for Mathematical Innovation and Discovery
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Date Issued |
2015-08-04T13:42
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Description |
As new technologies are providing us with ever-richer, more complex data sets that capture diverse yet complementary information about biological systems, our challenge is to move beyond simple correlations and explore the complex networks that drive biological systems. I will draw upon separate, but interwoven threads of network analysis that have proven very fruitful in our work, including inference and comparison of gene regulatory networks using a message-passing framework, exploring the diversity and distribution of networks within a phenotype and in state transitions, and exploring the structure of networks as a means of interpreting the factors driving complex, multifactorial phenotypes.
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Extent |
46 minutes
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Subject | |
Type | |
File Format |
video/mp4
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Language |
eng
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Notes |
Author affiliation: Dana-Farber Cancer Institute
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Series | |
Date Available |
2016-04-19
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Provider |
Vancouver : University of British Columbia Library
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Rights |
Attribution-NonCommercial-NoDerivatives 4.0 International
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DOI |
10.14288/1.0300005
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URI | |
Affiliation | |
Peer Review Status |
Unreviewed
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Scholarly Level |
Faculty
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Rights URI | |
Aggregated Source Repository |
DSpace
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Item Media
Item Citations and Data
Rights
Attribution-NonCommercial-NoDerivatives 4.0 International