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Statistical analysis of RNA-seq data at different scales Leek, Jeff
Description
RNA-seq is now the primary technology used to measure transcriptional abundance. The analysis of RNA-seq data can be done at multiple levels (genes, regions, or transcripts) and at multiple scales (small experiments or large population cohorts). I will discuss statistical challenges in developing and applying software for the analysis of RNA-seq data at multiple scales including reproducibility, statistical power, trust in genomic annotations, and detection and removal of artifacts. These issues are critical in the analysis of data from genomic experiments in general, but are particularly acute in the analysis of dynamic data from transcriptomes.
Item Metadata
Title |
Statistical analysis of RNA-seq data at different scales
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Creator | |
Publisher |
Banff International Research Station for Mathematical Innovation and Discovery
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Date Issued |
2015-08-03T09:47
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Description |
RNA-seq is now the primary technology used to measure transcriptional abundance. The analysis of RNA-seq data can be done at multiple levels (genes, regions, or transcripts) and at multiple scales (small experiments or large population cohorts). I will discuss statistical challenges in developing and applying software for the analysis of RNA-seq data at multiple scales including reproducibility, statistical power, trust in genomic annotations, and detection and removal of artifacts. These issues are critical in the analysis of data from genomic experiments in general, but are particularly acute in the analysis of dynamic data from transcriptomes.
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Extent |
32 minutes
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Type | |
File Format |
video/mp4
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Language |
eng
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Notes |
Author affiliation: Johns Hopkins Bloomberg School of Public Health
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Series | |
Date Available |
2016-04-18
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Provider |
Vancouver : University of British Columbia Library
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Rights |
Attribution-NonCommercial-NoDerivatives 4.0 International
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DOI |
10.14288/1.0300003
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URI | |
Affiliation | |
Peer Review Status |
Unreviewed
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Scholarly Level |
Faculty
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Rights URI | |
Aggregated Source Repository |
DSpace
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Item Citations and Data
Rights
Attribution-NonCommercial-NoDerivatives 4.0 International